Zestril (Lisinopril)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Zestril Used For?
Zestril is a medication that contains lisinopril, which is used primarily to manage high blood pressure, heart failure, and to support recovery after a heart attack.
Primary Uses
Zestril is used to treat hypertension (high blood pressure), heart failure, and to assist patients recovering from a heart attack.
Good to know: Zestril is not considered addictive.
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How to Take Zestril
Follow your doctor's instructions on how to take Zestril for optimal results.
Dosage Instructions
For high blood pressure, the usual starting dose is 5 mg to 10 mg once daily, with a typical maintenance dose of 10 mg to 20 mg daily. For heart failure, start with 2.5 mg once daily, increasing to 5 mg to 20 mg as needed. After a heart attack, start with 5 mg within 24 hours, followed by 5 mg after 24 hours, then 10 mg after 48 hours, and maintain at 10 mg daily.
What If You Miss a Dose?
If you miss a dose of Zestril, skip the missed dose and take your next dose at the scheduled time. Do not double up on doses.
Important: Never take a double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Mild stomach upset
- Dry cough
- Dizziness
- Headache
- Fatigue
- Changes in taste
Seek immediate medical attention if you experience:
- Chest pain
- Swelling of the face, lips, or throat
- Difficulty breathing
- Severe abdominal pain
- Yellowing of the skin or eyes
- Passing less urine than normal
- Signs of dehydration
Impulse Control Issues
There are no specific mentions of impulse control issues associated with Zestril.
Important Warnings
There are important considerations to keep in mind before using Zestril.
Who Should Not Take Zestril
Do not use Zestril if you have a history of allergic reactions to lisinopril or similar medications, are undergoing dialysis, or are taking aliskiren if you have diabetes or kidney issues.
Medical Conditions to Discuss
Discuss with your doctor if you have kidney problems, low blood pressure, liver issues, diabetes, or are on a very low salt diet.
Pregnancy and Breastfeeding
Zestril is not recommended during pregnancy or breastfeeding due to potential harm to the baby.
Elderly Patients With Dementia: Elderly patients should be monitored closely as they may be at higher risk for side effects.
Drug Interactions
Certain medications may interact with Zestril and affect its efficacy.
Grapefruit interaction: Consult your doctor regarding grapefruit consumption while on Zestril.
- Angiotensin II receptor blockers (e.g., candesartan, valsartan)
- Other blood pressure medications containing aliskiren
- Diuretics (water pills)
- Lithium
- Potassium supplements
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Heparin
- Sulfamethoxazole and trimethoprim
- Gold injections
- Insulin or diabetes medications
- mTOR inhibitors (e.g., temsirolimus, everolimus)
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Zestril.
Alcohol
Limit alcohol intake as advised by your doctor.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Zestril affects you.
Temperature Regulation
Ensure adequate hydration, especially in hot weather, to avoid dizziness.
Storage
Store Zestril below 30°C in a cool, dry place away from moisture and out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Symptoms may include light-headedness or fainting.
Frequently Asked Questions
Zestril may take several weeks to fully lower blood pressure.
You can take Zestril with or without food.
No, Zestril is not considered addictive.
Consult your doctor before stopping Zestril, as sudden discontinuation may lead to increased blood pressure.
It's advisable to limit alcohol intake while on Zestril.
Weight gain is not a common side effect of Zestril.
Elderly patients should be monitored closely for side effects.
If you miss a dose, skip it and take your next dose at the scheduled time.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.