Cabenuva (Cabotegravir And Rilpivirine)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Cabenuva Used For?
Cabenuva is a combination medication used to manage HIV infection in adults aged 18 and older.
Primary Uses
It is primarily used to treat Human Immunodeficiency Virus (HIV) infection.
How It Works
Cabotegravir is an integrase inhibitor, while rilpivirine is a non-nucleoside reverse transcriptase inhibitor. Together, they help maintain low levels of the virus in the body.
Good to know: Cabenuva is not addictive.
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How to Take Cabenuva
Cabenuva is administered as intramuscular injections, either monthly or bi-monthly, by a healthcare professional.
Dosage Instructions
Initially, you may receive a lead-in treatment with VOCABRIA tablets for one month before starting Cabenuva injections. The injections consist of cabotegravir 600 mg and rilpivirine 900 mg, given as two injections.
What If You Miss a Dose?
If you miss an appointment for your injections, contact your doctor immediately to reschedule. You may need to take oral medications until your next injection.
Important: Do not stop taking Cabenuva without consulting your doctor.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- injection site reactions
- feeling hot
- depression
- anxiety
- abnormal dreams
- insomnia
- dizziness
- nausea
- vomiting
- stomach pain
- diarrhoea
- rash
- muscle pain
- chest or back pain
- fatigue
Seek immediate medical attention if you experience:
- allergic reactions
- liver problems
- Stevens-Johnson syndrome
- toxic epidermal necrolysis
Important Warnings
There are several important considerations before starting Cabenuva.
Who Should Not Take Cabenuva
Do not use Cabenuva if you are allergic to cabotegravir, rilpivirine, or any of its ingredients. Avoid it if you are taking certain medications like rifampicin or anticonvulsants.
Medical Conditions to Discuss
Inform your doctor if you have liver or kidney problems, as these may affect your treatment.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant or planning to become pregnant. It is not recommended to breastfeed while on Cabenuva due to potential risks.
Drug Interactions
Certain medications may interact with Cabenuva, affecting its efficacy.
- rifampicin
- rifapentine
- carbamazepine
- oxcarbazepine
- phenobarbital
- phenytoin
- St. John's wort
- clarithromycin
- erythromycin
- methadone
- dexamethasone
Alcohol & Driving
Be cautious with alcohol and operating machinery while on Cabenuva.
Alcohol
Consult your doctor about alcohol consumption while on treatment.
Driving and Operating Machinery
Cabenuva may cause dizziness; do not drive or operate machinery until you know how it affects you.
Temperature Regulation
Monitor your body temperature, as Cabenuva may cause feelings of being hot.
Storage
Store Cabenuva in the refrigerator at 2°C to 8°C and keep it in its original packaging until use. Do not freeze.
Overdose Information
Overdose is unlikely as injections are administered by a healthcare professional. If you suspect an overdose, contact your doctor.
Frequently Asked Questions
Cabenuva helps control HIV infection but does not cure it. Regular treatment is essential.
There are no specific dietary restrictions mentioned for Cabenuva.
No, Cabenuva is not considered addictive.
Stopping Cabenuva without consulting your doctor may lead to viral resistance and worsening of your condition.
Consult your doctor regarding alcohol consumption while on Cabenuva.
Weight gain is not specifically mentioned as a side effect of Cabenuva.
Elderly patients should discuss their overall health and any existing conditions with their doctor before starting Cabenuva.
Contact your doctor immediately to reschedule your injection if you miss an appointment.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.