Caprelsa (Vandetanib)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Caprelsa Used For?
Caprelsa contains the active ingredient vandetanib and is used to treat medullary thyroid cancer, especially when it has spread to other areas of the body.
Primary Uses
Medullary thyroid cancer, particularly in metastatic cases.
How It Works
Caprelsa works by inhibiting the growth of new blood vessels in tumors, thereby limiting their supply of nutrients and oxygen. It may also directly affect cancer cells to slow their growth or kill them.
Good to know: Caprelsa is not addictive.
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How to Take Caprelsa
Follow your doctor's instructions carefully when taking Caprelsa.
Dosage Instructions
The usual dose is 300 mg once daily, taken as three 100 mg tablets. If you have kidney issues, your doctor may prescribe a lower dose of 200 mg daily.
What If You Miss a Dose?
If it's less than 12 hours until your next dose, skip the missed dose and take your next dose as scheduled. Do not double up.
Important: Never double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- mild diarrhoea
- nausea
- vomiting
- loss of appetite
- weight loss
- dehydration
- skin rash/acne
- skin sensitivity to sunlight
- tiredness
- fatigue
Seek immediate medical attention if you experience:
- severe diarrhoea
- severe skin reactions
- breathlessness
- changes in heart rhythm
- stroke symptoms
- severe headache
- renal failure
Important Warnings
There are specific warnings and contraindications to consider before taking Caprelsa.
Who Should Not Take Caprelsa
Do not take Caprelsa if you are allergic to vandetanib or any of its ingredients, or if you have congenital long QT syndrome.
Medical Conditions to Discuss
Discuss any history of heart problems, kidney issues, liver problems, or if you plan to have surgery with your doctor.
Pregnancy and Breastfeeding
Caprelsa may harm an unborn child. Women who are pregnant or may become pregnant should not take Caprelsa. Effective contraception is required during treatment and for at least four months after the last dose. Breastfeeding is not recommended while taking Caprelsa.
Drug Interactions
Some medications may affect how Caprelsa works or be affected by it.
- itraconazole
- ketoconazole
- ritonavir
- clarithromycin
- rifampicin
- carbamazepine
- phenobarbital
- ondansetron
- haloperidol
- chlorpromazine
- vitamin K antagonists
- dabigatran
- cyclosporin
- tacrolimus
- digoxin
- metformin
- cisapride
- proton pump inhibitors
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while on Caprelsa.
Alcohol
Consult your doctor if you consume alcohol.
Driving and Operating Machinery
Caprelsa may cause tiredness and blurred vision. Avoid driving or using machinery if you experience these symptoms.
Temperature Regulation
Caprelsa may increase sensitivity to sunlight; take precautions to avoid sunburn.
Storage
Store Caprelsa in a cool, dry place below 30°C, away from moisture and sunlight. Keep out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Symptoms may include increased severity of side effects like rash, diarrhoea, and heart issues.
Frequently Asked Questions
The time it takes for Caprelsa to work can vary by individual. Consult your doctor for more specific information.
It does not matter if you take Caprelsa before or after food.
No, Caprelsa is not considered addictive.
Do not stop taking Caprelsa without consulting your doctor, as it may worsen your condition.
Consult your doctor if you consume alcohol while on Caprelsa.
Weight changes can occur; consult your doctor if you have concerns.
Elderly patients should discuss their health status with their doctor before starting Caprelsa.
If it's less than 12 hours until your next dose, skip the missed dose and take your next dose as scheduled.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.