Benlysta (Belimumab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Benlysta Used For?
Benlysta is a medication containing belimumab, used primarily for treating lupus, a disease affecting the immune system.
Primary Uses
Benlysta is used to treat systemic lupus erythematosus (SLE) and active lupus nephritis in adults.
How It Works
Benlysta works by binding to a protein called BLyS, which is often present in high levels in people with lupus, thereby limiting its activity.
Good to know: Benlysta is not addictive.
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How to Take Benlysta
Benlysta can be administered either through an intravenous infusion or as a subcutaneous injection.
Dosage Instructions
For intravenous infusion, the usual dose is 10 mg per kg of body weight. For subcutaneous injection, the recommended dose is 200 mg once a week, or 400 mg (two 200 mg injections) once a week for the first four doses if treating lupus nephritis.
What If You Miss a Dose?
If you miss a subcutaneous injection, administer it as soon as possible and then return to your regular schedule.
Important: Never double the dose if you miss one.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- rash at the injection site
- nausea
- diarrhea
- fever
- pain in hands and feet
Seek immediate medical attention if you experience:
- serious infections (e.g., chest, bladder, or stomach infections)
- allergic reactions (e.g., difficulty breathing, swelling of face or mouth)
- depression and suicidal thoughts
- low white blood cell count
Important Warnings
There are several important warnings to consider before using Benlysta.
Who Should Not Take Benlysta
Do not use Benlysta if you have had an allergic reaction to belimumab or any of its ingredients.
Medical Conditions to Discuss
Discuss any history of depression, suicidal thoughts, infections, or if you are taking other medications with your doctor.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Benlysta may pass into breast milk.
Drug Interactions
Some medications may interfere with how Benlysta works.
Alcohol & Driving
Be cautious with alcohol consumption and driving while using Benlysta.
Alcohol
Consult your doctor about alcohol use while on Benlysta.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Benlysta affects you.
Storage
Store Benlysta in a refrigerator at 2°C to 8°C and protect it from light. Do not freeze.
Overdose Information
If you suspect an overdose, seek immediate medical attention by contacting your doctor or going to the nearest hospital.
Frequently Asked Questions
The time it takes for Benlysta to show effects can vary by individual, but it is typically administered over several weeks.
There are no specific dietary restrictions mentioned for Benlysta.
No, Benlysta is not considered addictive.
Consult your doctor before stopping Benlysta, as they will provide guidance on how to proceed.
Discuss alcohol consumption with your doctor while on Benlysta.
Weight gain is not listed as a common side effect of Benlysta.
Elderly patients should discuss their overall health and any pre-existing conditions with their doctor before taking Benlysta.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.