Pluvicto (Lutetium (177Lu) Vipivotide Tetraxetan)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Pluvicto Used For?
Pluvicto is a medication used to treat advanced prostate cancer that has spread to other parts of the body and has not responded to other treatments.
Primary Uses
It is primarily used for metastatic castration-resistant prostate cancer.
How It Works
Pluvicto contains a radioactive substance that targets and destroys cancer cells by delivering radiation directly to them.
Good to know: Pluvicto is not addictive.
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How to Take Pluvicto
Pluvicto is administered in a controlled medical environment by trained professionals.
Dosage Instructions
The recommended dose is 7,400 MBq given intravenously once every 6 weeks for up to six doses.
What If You Miss a Dose?
If you miss an appointment for your dose, contact your specialist as soon as possible to reschedule.
Important: Never double the dose if you miss an appointment.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Tiredness
- Abdominal pain
- Constipation
- Diarrhea
- Urinary tract infection
- Headache
- Nausea
- Dizziness
- Dry mouth
- Difficulty swallowing
- Heartburn
- Decreased appetite
- Weight loss
- Swelling of hands, ankles, or feet
- Dry eye
- Oral fungal infection
- Mouth sores
- Dry skin
- Vomiting
Seek immediate medical attention if you experience:
- Unusual bruising
- Extreme tiredness
- Weakness
- Pale skin
- Shortness of breath
- Reduced urine output
- Fever
- Chills
- Sore throat
- Mouth ulcers
Impulse Control Issues
There are no specific mentions of impulse control issues related to Pluvicto.
Important Warnings
There are several important warnings to consider before taking Pluvicto.
Who Should Not Take Pluvicto
Do not use Pluvicto if you are allergic to lutetium (177Lu) vipivotide tetraxetan or any of its ingredients.
Medical Conditions to Discuss
Discuss any history of kidney problems, other cancers, or low blood cell counts with your specialist.
Pregnancy and Breastfeeding
Pluvicto can harm an unborn baby. Limit close contact with pregnant women for 7 days after each dose.
Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.
Drug Interactions
Some medications may interact with Pluvicto, affecting its efficacy.
Grapefruit interaction: Consult your doctor if you consume grapefruit products.
- Other cancer treatments
- Over-the-counter medications
- Supplements
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while on Pluvicto.
Alcohol
Inform your specialist if you consume alcohol.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Pluvicto affects you, as it may cause fatigue.
Temperature Regulation
There are no specific warnings related to temperature regulation.
Storage
Pluvicto must be stored by the specialist below 30°C and in its original packaging to protect from radiation.
Overdose Information
In the unlikely event of an overdose, contact your specialist or the Poisons Information Centre at 13 11 26 immediately.
Frequently Asked Questions
The effects of Pluvicto may vary, but it is administered every 6 weeks for optimal results.
There are no specific instructions regarding food, but it is administered in a medical setting.
No, Pluvicto is not considered addictive.
Consult your specialist for guidance if you are considering stopping treatment.
It is advised to inform your specialist if you consume alcohol.
Weight gain is not listed as a common side effect of Pluvicto.
Elderly patients should be cautious, especially those with dementia.
Contact your specialist as soon as possible to reschedule if you miss an appointment.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.