Pergoveris solution for injection (Follitropin Alfa And Lutropin Alfa)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Pergoveris solution for injection Used For?
Pergoveris is a medication that contains two active ingredients, follitropin alfa and lutropin alfa, which are hormones similar to those naturally produced in the body. It is primarily used to stimulate the development of follicles in women who have a severe deficiency of luteinizing hormone (LH) and follicle-stimulating hormone (FSH).
Primary Uses
It is used for stimulating follicular development in women with severe LH and FSH deficiency.
How It Works
Pergoveris works by providing the body with the hormones necessary for follicular growth, which is essential for ovulation and fertility.
Good to know: Pergoveris is not addictive.
Continue Reading
Sign in to access the complete medication guide including dosage, side effects, warnings, and more.
How to Take Pergoveris solution for injection
Pergoveris is administered as a daily injection under the skin, typically in the lower abdominal area or thigh.
Dosage Instructions
The usual starting dose is 150 IU of follitropin alfa and 75 IU of lutropin alfa, injected once daily. Your doctor will adjust the dosage based on your individual response.
What If You Miss a Dose?
If you miss a dose, contact your doctor or nurse immediately for advice.
Important: Do not double the dose if you miss one.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- injection site reactions (bruising, pain, redness, itching, swelling)
- headache
- dizziness
- ovarian enlargement or cysts
- nausea
- vomiting
- diarrhea
- abdominal discomfort
Seek immediate medical attention if you experience:
- allergic reactions (severe skin rash, swelling, difficulty breathing)
- Ovarian Hyperstimulation Syndrome (OHSS) with symptoms like lower abdominal pain, rapid weight gain, low urine output
- thromboembolism (blood clots) with symptoms like pain, warmth, or numbness in limbs
Important Warnings
There are several important warnings to consider before using Pergoveris.
Who Should Not Take Pergoveris solution for injection
Do not use Pergoveris if you are allergic to gonadotrophins or any ingredients in this medication, if you are pregnant or breastfeeding, or if you have certain medical conditions such as unexplained ovarian enlargement, vaginal bleeding, or cancers of the reproductive organs.
Medical Conditions to Discuss
Discuss with your doctor if you have conditions such as premature menopause, thyroid disorders, kidney or liver disease, or a family history of blood clots.
Pregnancy and Breastfeeding
Do not use Pergoveris if you are pregnant or breastfeeding. If you become pregnant while using it, inform your doctor immediately.
Drug Interactions
Some medications may interact with Pergoveris and affect its effectiveness. Always inform your doctor about any other medications you are taking.
Alcohol & Driving
Be cautious when driving or operating machinery until you know how Pergoveris affects you.
Alcohol
There are no specific warnings about alcohol consumption mentioned, but it is advisable to consult your doctor.
Driving and Operating Machinery
Exercise caution when driving or using machines until you are aware of how this medication affects you.
Storage
Store Pergoveris in its original package in a refrigerator at 2°C to 8°C. Do not freeze. After the first injection, it can be kept at room temperature (below 25°C) for up to 28 days.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26.
Frequently Asked Questions
The time it takes for Pergoveris to work can vary based on individual response and treatment plans.
There are no specific instructions regarding food interactions, but it is best to follow your doctor's advice.
No, Pergoveris is not considered addictive.
Do not stop using Pergoveris suddenly without consulting your doctor, as it may affect your treatment.
Consult your doctor regarding alcohol consumption while on this medication.
Weight gain is not specifically mentioned as a side effect, but consult your doctor if you have concerns.
Elderly patients should discuss their health conditions with their doctor before using Pergoveris.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.