Opdivo (Nivolumab)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
nivolumab
Drug Class
immunotherapy
Used For
treating various types of cancer
How Taken
administered as an intravenous infusion in a hospital or clinic

What Is Opdivo Used For?

Opdivo is a medication that helps the immune system fight cancer by targeting specific proteins.

Primary Uses

Opdivo is used to treat advanced skin cancer (unresectable or metastatic melanoma), advanced lung cancer (squamous and non-squamous non-small cell lung cancer), clear cell renal cell carcinoma, squamous cell cancer of the head and neck, classical Hodgkin lymphoma, urothelial carcinoma, hepatocellular carcinoma, oesophageal squamous cell cancer, and various other cancers in combination with other treatments.

How It Works

Opdivo works by enhancing the body's immune response against cancer cells, allowing the immune system to recognize and destroy them.

Good to know: Opdivo is not considered addictive.

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How to Take Opdivo

Opdivo is given as an infusion in a clinical setting under the supervision of healthcare professionals.

Dosage Instructions

The dosage and frequency of Opdivo depend on the type of cancer being treated. Your doctor will determine the appropriate treatment plan.

What If You Miss a Dose?

It is important to keep all scheduled appointments for Opdivo treatment. If you miss an appointment, consult your doctor to reschedule.

Important: Never double the dose if you miss an appointment.

Available Tablet Strengths

5mg
5mg Tablet Blue, Round • A-007
10mg
10mg Tablet Pink, Rectangular • A-008
15mg
15mg Tablet Yellow, Round • A-009
20mg
20mg Tablet White, Round • A-010
30mg
30mg Tablet Pink, Round • A-011

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Diarrhoea
  • Nausea
  • Skin rash
  • Fatigue
  • Decreased appetite

Seek immediate medical attention if you experience:

  • Lung problems (breathing difficulties)
  • Inflammation of the intestines
  • Liver inflammation
  • Kidney inflammation
  • Hormonal gland issues
  • Severe skin reactions
  • Nerve damage
  • Heart inflammation
  • Serious allergic reactions

Important Warnings

Certain precautions and contraindications should be considered before using Opdivo.

Who Should Not Take Opdivo

Do not use Opdivo if you have a known allergy to nivolumab or any of its ingredients.

Medical Conditions to Discuss

Discuss with your doctor if you have autoimmune diseases, a history of lung inflammation, or if your cancer has spread to the brain.

Pregnancy and Breastfeeding

Opdivo should not be used during pregnancy unless specifically recommended by your doctor. It is also advised to stop breastfeeding while receiving treatment.

Drug Interactions

Some medications may interfere with how Opdivo works.

  • Corticosteroids
  • Other immunosuppressants

Alcohol & Driving

While Opdivo is unlikely to impair your ability to drive or operate machinery, caution is advised.

Alcohol

Consult your doctor regarding alcohol consumption while on Opdivo.

Driving and Operating Machinery

Use caution when driving or operating machinery until you know how Opdivo affects you.

Storage

Opdivo should be stored in a controlled environment as determined by your healthcare provider.

Overdose Information

Opdivo is administered by healthcare professionals, making overdose unlikely. If you experience side effects, inform your doctor immediately.

Frequently Asked Questions

The time it takes for Opdivo to show effects can vary based on the individual and the type of cancer being treated.

Opdivo is administered as an infusion, so food intake does not affect its administration.

No, Opdivo is not considered addictive.

Consult your doctor before making any changes to your treatment plan, as stopping suddenly may affect your health.

It is advisable to consult your doctor regarding alcohol consumption while on Opdivo.

Weight changes can occur, but it is important to discuss any concerns with your doctor.

Elderly patients should discuss their overall health and any specific concerns with their doctor before starting Opdivo.

If you miss an appointment for Opdivo, consult your doctor to reschedule your next dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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