Omjjara (Momelotinib)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name

momelotinib

Drug Class

protein kinase inhibitor

Used For

treating adults with myelofibrosis and associated anemia

How Taken

oral tablet once daily

What Is Omjjara Used For?

Omjjara is a medication that contains momelotinib, which is used to manage myelofibrosis, a rare blood cancer affecting the bone marrow. It helps reduce spleen size and alleviate symptoms associated with the disease.

Primary Uses

Omjjara is primarily used to treat adults with myelofibrosis, especially those who also have anemia.

How It Works

Omjjara works by blocking certain proteins (JAK1, JAK2, and ACVR1) that contribute to the symptoms of myelofibrosis, helping to restore normal blood cell production.

Good to know: Omjjara is not considered addictive.

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How to Take Omjjara

Take Omjjara exactly as prescribed by your healthcare provider. It can be taken with or without food.

Dosage Instructions

The recommended dosage for adults is 200 mg taken orally once daily.

What If You Miss a Dose?

If you miss a dose, skip it and take your next dose at the scheduled time. Do not take a double dose.

Important: Never double the dose if you miss one.

Available Tablet Strengths

100 mg

100 mg Tablet Brown, Round • M 100

150 mg

150 mg Tablet Brown, Triangle • M 150

200 mg

200 mg Tablet Brown, Capsule • M 200

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

diarrhea
low platelets
nausea
headache
dizziness
fatigue
weakness
abdominal pain
rash
cough

Seek immediate medical attention if you experience:

infections
low blood platelet count
low levels of white blood cells
liver problems indicated by blood test changes

Impulse Control Issues

There may be risks related to impulse control, including gambling or spending issues.

Important Warnings

There are several important warnings to consider before taking Omjjara.

Who Should Not Take Omjjara

Do not take Omjjara if you have had an allergic reaction to momelotinib or any of its ingredients.

Medical Conditions to Discuss

Discuss any history of heart problems, stroke, hepatitis B, or liver issues with your doctor.

Pregnancy and Breastfeeding

If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor as Omjjara may harm your baby. Effective contraception is required during treatment and for at least 1 week after the last dose.

Elderly Patients With Dementia: Elderly patients may be at increased risk for heart problems and should be monitored closely.

Drug Interactions

Certain medications may interact with Omjjara and affect its effectiveness.

Grapefruit interaction: Consult your doctor about potential interactions with grapefruit.

rosuvastatin
carbamazepine
phenobarbital
phenytoin
St John’s wort

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while on Omjjara.

Alcohol

Inform your doctor if you consume alcohol, as it may affect your treatment.

Driving and Operating Machinery

Omjjara may cause dizziness or blurred vision; use caution when driving or operating machinery.

Storage

Store Omjjara in a cool, dry place away from moisture and sunlight. Keep it in the original bottle with the desiccant until ready to use.

Overdose Information

In case of overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

The time it takes for Omjjara to show effects can vary by individual, but it is important to follow your doctor's guidance.

Yes, Omjjara can be taken with or without food.

No, Omjjara is not considered addictive.

Do not stop taking Omjjara without consulting your doctor, as it may lead to a return of symptoms.