Nexium (Esomeprazole Magnesium Trihydrate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
esomeprazole magnesium trihydrate
Drug Class
proton-pump inhibitor
Used For
treating reflux oesophagitis, peptic ulcers, and other gastrointestinal conditions
How Taken
oral tablets or granules, typically once daily

What Is Nexium Used For?

Nexium is a medication that reduces stomach acid production, helping to relieve symptoms and promote healing of various gastrointestinal conditions.

Primary Uses

Nexium is primarily used to treat reflux oesophagitis, upper gastrointestinal symptoms related to NSAID therapy, peptic ulcers associated with Helicobacter pylori infection, Zollinger-Ellison syndrome, and bleeding peptic ulcers.

How It Works

Nexium works by decreasing the amount of acid produced in the stomach, which helps alleviate symptoms and allows for healing.

Good to know: Nexium is not considered addictive.

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How to Take Nexium

Nexium can be taken as tablets or granules for suspension. It's important to follow your doctor's instructions regarding dosage.

Dosage Instructions

The usual dose for Nexium tablets is 20 mg or 40 mg daily, while the sachets are typically 10 mg to 20 mg daily, depending on the condition being treated.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and return to your regular schedule. Do not double up on doses.

Important: Never take a double dose to make up for a missed dose.

Available Tablet Strengths

20mg
20mg Tablet Light pink, Oblong • 20 mg
40mg
40mg Tablet Pink, Oblong • 40 mg
10mg
10mg Tablet Pale yellow, Fine granules • sachet

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • nausea
  • vomiting
  • constipation
  • diarrhea
  • headache
  • stomach pain
  • skin rash
  • itchy skin
  • dizziness
  • dry mouth

Seek immediate medical attention if you experience:

  • shortness of breath
  • wheezing
  • swelling of the face or lips
  • severe skin reactions
  • liver inflammation signs
  • blood in urine
  • changes in urine output

Impulse Control Issues

There is no mention of impulse control issues related to Nexium.

Important Warnings

There are specific warnings to consider before using Nexium.

Who Should Not Take Nexium

Do not take Nexium if you are allergic to esomeprazole or any of its ingredients, or if you are taking atazanavir or cilostazol.

Medical Conditions to Discuss

Discuss any allergies, liver problems, severe kidney issues, and a history of osteoporosis with your doctor.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as the safety of Nexium during these times is not fully established.

Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.

Drug Interactions

Certain medications may interact with Nexium, affecting its effectiveness.

Grapefruit interaction: Grapefruit may affect how Nexium works.

  • Atazanavir
  • Nelfinavir
  • Cilostazol
  • Ketoconazole
  • Itraconazole
  • Voriconazole
  • Diazepam
  • Phenytoin
  • Citalopram
  • Clomipramine
  • Imipramine
  • St John's wort
  • Clarithromycin
  • Rifampicin
  • Warfarin
  • Clopidogrel
  • Digoxin
  • Methotrexate
  • Tacrolimus
  • Mycophenolate mofetil
  • Serlotinib

Alcohol & Driving

Be cautious with alcohol and driving while taking Nexium.

Alcohol

Consult your doctor regarding alcohol consumption while on Nexium.

Driving and Operating Machinery

Be careful when driving or using machinery until you know how Nexium affects you.

Storage

Store Nexium in its original blister pack or sachet in a cool, dry place below 25°C, away from moisture and heat.

Overdose Information

If you suspect an overdose of Nexium, seek immediate medical attention or contact the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

Nexium typically relieves symptoms rapidly, with healing usually complete within 4 weeks.

Nexium can be taken with or without food.

No, Nexium is not considered addictive.

Consult your doctor before stopping Nexium, as it may not prevent the recurrence of symptoms.

It's advisable to consult your doctor regarding alcohol consumption while on Nexium.

There is no specific information regarding weight gain associated with Nexium.

Elderly patients should use Nexium with caution, especially those with dementia.

If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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