Mesasal (Mesalazine)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
mesalazine
Drug Class
salicylates
Used For
treatment of acute inflammatory bowel disease, Crohn's disease, and ulcerative colitis
How Taken
oral tablet, typically two tablets three times a day for acute conditions, one tablet three times a day for maintenance

What Is Mesasal Used For?

Mesasal contains mesalazine and is prescribed to manage inflammation in the large intestine associated with certain bowel diseases.

Primary Uses

It is primarily used to treat acute inflammatory bowel disease, Crohn's disease, and ulcerative colitis.

How It Works

Mesalazine works by suppressing inflammation in the large intestine.

Good to know: Mesasal is not addictive.

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How to Take Mesasal

Follow your doctor's instructions on how to take Mesasal for optimal results.

Dosage Instructions

For acute ulcerative colitis and Crohn's disease, the usual dosage is two tablets three times daily. For maintenance or to prevent relapses, take one tablet three times daily. Always take the tablets at least 30 minutes before meals.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take a double dose.

Important: Never double dose to make up for a missed dose.

Available Tablet Strengths

5mg
5mg Tablet Tan, Round
10mg
10mg Tablet Tan, Round
15mg
15mg Tablet Tan, Round
20mg
20mg Tablet Tan, Round
30mg
30mg Tablet Tan, Round

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • headache
  • mild stomach pains
  • excessive gas
  • increased bowel movements
  • diarrhea
  • nausea
  • rash
  • common cold

Seek immediate medical attention if you experience:

  • fever
  • muscle aches
  • painful joints
  • chest pain
  • severe upper stomach pain
  • numbness or weakness in limbs
  • difficulty breathing or swallowing
  • serious skin reactions like DRESS, SJS, or TEN

Important Warnings

There are specific warnings and contraindications to consider before taking Mesasal.

Who Should Not Take Mesasal

Do not take Mesasal if you are allergic to mesalazine or any aspirin-like medicines, have severe kidney issues, a bleeding disorder, a stomach or duodenal ulcer, or are in the last weeks of pregnancy.

Medical Conditions to Discuss

Discuss with your doctor if you have kidney or liver problems, lung issues like asthma, or if you've had allergic reactions to similar medications.

Pregnancy and Breastfeeding

Do not take Mesasal if you are pregnant or breastfeeding, as it may affect your baby.

Drug Interactions

Certain medications may interact with Mesasal.

  • anti-coagulant medicines like warfarin
  • glucocorticoids such as prednisolone
  • oral hypoglycemics for diabetes
  • probenecid and sulfinpyrazone
  • spironolactone and furosemide
  • rifampicin
  • immunosuppressants like methotrexate, azathioprine, or 6-mercaptopurine

Alcohol & Driving

Be cautious with alcohol and operating machinery while on Mesasal.

Alcohol

Inform your doctor if you consume alcohol.

Driving and Operating Machinery

Mesasal is not expected to impair your ability to drive or operate machinery, but be cautious until you know how it affects you.

Storage

Store Mesasal tablets in a cool, dry place below 25°C, away from moisture and light, and keep out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention or contact the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

The time it takes for Mesasal to work can vary by individual, but it is important to continue taking it as prescribed for the best results.

It is recommended to take Mesasal at least 30 minutes before meals.

No, Mesasal is not considered addictive.

Do not stop taking Mesasal suddenly without consulting your doctor, as it may worsen your condition.

You should inform your doctor if you consume alcohol while taking Mesasal.

Weight gain is not listed as a common side effect of Mesasal.

Elderly patients should discuss their overall health with their doctor before taking Mesasal.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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