Maviret (Glecaprevir And Pibrentasvir)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
glecaprevir and pibrentasvir
Drug Class
Antiviral
Used For
Treatment of chronic hepatitis C
How Taken
Oral tablets, three tablets once daily with food

What Is Maviret Used For?

Maviret is an antiviral medication used to treat chronic hepatitis C in patients aged 3 years and older.

Primary Uses

It is primarily used to manage chronic hepatitis C.

How It Works

Maviret works by inhibiting the replication of the hepatitis C virus.

Good to know: Maviret is not considered addictive.

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How to Take Maviret

Maviret should be taken as directed by your healthcare provider.

Dosage Instructions

For patients 12 years and older, take three tablets together once daily with food. For children aged 3 to less than 12 years, the dosage will be prescribed based on weight, using granules mixed with food.

What If You Miss a Dose?

If you miss a dose and it's less than 6 hours until your next dose, skip the missed dose. If it's 6 hours or more, take the missed dose and continue with your regular schedule.

Important: Never double the dose to make up for a missed dose.

Available Tablet Strengths

5mg
5mg Tablet Blue, Round • A-007
10mg
10mg Tablet Pink, Rectangular • A-008
15mg
15mg Tablet Yellow, Round • A-009
20mg
20mg Tablet White, Round • A-010
30mg
30mg Tablet Pink, Round • A-011

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Fatigue
  • Headache
  • Nausea
  • Itchy skin

Seek immediate medical attention if you experience:

  • Swelling of the face, lips, mouth, tongue, or throat which may cause difficulty swallowing or breathing

Important Warnings

There are specific warnings to consider before taking Maviret.

Who Should Not Take Maviret

Do not take Maviret if you are allergic to glecaprevir, pibrentasvir, or any other ingredients, have moderate to severe liver disease, or are taking certain medications such as atazanavir, atorvastatin, simvastatin, dabigatran etexilate, ethinylestradiol-containing products, or rifampicin.

Medical Conditions to Discuss

Inform your doctor if you have liver conditions other than hepatitis C, HIV, hepatitis B, a history of liver or kidney transplants, diabetes, or are taking any other medications.

Pregnancy and Breastfeeding

Notify your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Drug Interactions

Certain medications may interact with Maviret.

  • Atazanavir
  • Atorvastatin
  • Simvastatin
  • Dabigatran
  • Ethinylestradiol
  • Rifampicin

Alcohol & Driving

Precautions regarding alcohol consumption and driving while on Maviret.

Alcohol

There is no specific information on the effects of alcohol while taking Maviret.

Driving and Operating Machinery

Maviret is expected to have little to no effect on your ability to drive or operate machinery.

Storage

Store Maviret in a cool, dry place away from moisture, heat, and sunlight. Keep tablets in their original packaging until it's time to take them.

Overdose Information

If you suspect an overdose, contact the Poisons Information Centre at 13 11 26, your doctor, or go to the nearest Emergency Department immediately.

Frequently Asked Questions

Maviret typically starts to work after a few weeks of treatment, but the exact duration may vary based on individual response.

Yes, Maviret should be taken with food for optimal absorption.

No, Maviret is not considered an addictive medication.

Do not stop taking Maviret suddenly without consulting your doctor, as it may affect your treatment outcome.

There is no specific information regarding alcohol consumption while taking Maviret, but it's best to consult your doctor.

Weight gain is not commonly reported as a side effect of Maviret.

Elderly patients should discuss their overall health with their doctor to ensure Maviret is safe for them.

If you miss a dose, follow the instructions for missed doses provided in the medication guide.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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