Lozanoc (Itraconazole)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Lozanoc Used For?
Lozanoc contains itraconazole, an antifungal medication that treats various types of fungal infections throughout the body.
Primary Uses
Lozanoc treats persistent infections of the nails, skin, hands, feet, or groin; persistent candida (yeast) infections of the vagina; eye infections that haven’t responded to other treatments or may affect vision; candida infections of the mouth or throat in patients with weakened immune systems; and generalized fungal infections.
How It Works
Lozanoc works by killing or stopping the growth of the fungus that causes the infection.
Important: DO NOT SUBSTITUTE Lozanoc with other brands of itraconazole, as they are not interchangeable. Lozanoc has higher absorption than other itraconazole capsules and requires different dosing.
How to Take Lozanoc
Take only the number of Lozanoc capsules prescribed by your doctor. Lozanoc can be taken before or after meals and should be taken regularly at the same time each day.
Dosage Instructions
Dosages vary by condition: Tinea of body & groin: 1 capsule daily for 2 weeks. Tinea of hands & feet: 1 capsule daily for 4 weeks. Other skin infections: 2 capsules daily for 1 week. Eye infections: 2 capsules daily for 3 weeks. Vaginal infections: 2 capsules morning & evening for 1 day, or 2 capsules daily for 3 days. Mouth infections: 1-2 capsules daily for 4 weeks. Systemic infections: 1-2 capsules once or twice daily for 3 weeks to 8 months. Nail infections: Continuous therapy: 2 capsules daily for 3 months, or Cyclic therapy: 2 capsules twice daily for 1 week, then stop for 3 weeks, repeat cycle.
What If You Miss a Dose?
If it’s almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take a double dose to make up for the missed one.
Important: Never take a double dose to make up for a missed dose. Complete the full treatment course even if infection signs disappear.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Stomach upset, pain, or discomfort
- Nausea and vomiting
- Diarrhea or constipation
- Unpleasant taste in mouth
- Shortness of breath
- Headache and dizziness
- Fever, confusion, cough, chills
- Changes in menstrual pattern
- Hair loss or thinning
- Erectile dysfunction
- Muscle weakness or pain
- Painful joints, tremors
- High or low blood pressure
Seek immediate medical attention if you experience:
- Tingling, numbness, or weakness in hands or feet
- Swelling of hands, ankles, feet, legs, or abdomen
- Shortness of breath, unexpected weight gain, unusual fatigue, or waking up at night
- Oversensitivity to sunlight
- Blurry or double vision, ringing in ears
- Loss of bladder control or increased urination
- Abnormal tiredness, loss of appetite, nausea, vomiting, dark urine, pale stools, yellowing of skin or eyes
- Sudden allergic reactions (rash, itching, hives, swelling of face/lips/tongue, breathing difficulties)
- Severe skin disorders (widespread rashes with peeling skin and blisters)
- Any hearing loss symptoms
Important Warnings
Several important warnings apply to Lozanoc use, including contraindications and special precautions for certain medical conditions.
Who Should Not Take Lozanoc
Do not take Lozanoc if you are allergic to itraconazole or any ingredients; have heart failure (congestive heart failure); are pregnant or may become pregnant; or are taking certain medications including terfenadine, astemizole, mizolastine, bepridil, felodipine, nisoldipine, lercanidipine, ranolazine, eplerenone, ivabradine, apixaban, rivaroxaban, dabigatran, cisapride, domperidone, levomethadyl, methadone, pimozide, lurasidone, sertindole, ticagrelor, halofantrine, isavuconazole, naloxegol, avanafil, dapoxetine, eliglustat, irinotecan, mobocertinib, venetoclax (in certain patients), midazolam oral, triazolam, simvastatin, lomitapide, lovastatin, dronedarone, dofetilide, quinidine, disopyramide, dihydroergotamine, ergotamine, fesoterodine and solifenacin (in patients with liver/kidney disease), colchicine (in patients with severe liver/kidney disease), telithromycin (in patients with severe liver/kidney disease), ergometrine, methylergometrine, finerenone, or voclosporin.
Medical Conditions to Discuss
Tell your doctor if you have liver or kidney problems, allergic reactions to other antifungal medicines, heart problems, neutropenia or AIDS or organ transplant, hearing problems, nerve damage with weakness/numbness/pain in hands and feet, or cystic fibrosis.
Pregnancy and Breastfeeding
Do not take Lozanoc if pregnant or may become pregnant. If there’s any chance of pregnancy, discuss highly effective contraception with your doctor. Continue contraception until your next period after finishing Lozanoc. Tell your doctor immediately if you become pregnant. Discuss risks and benefits with your doctor if breastfeeding or planning to breastfeed.
Not recommended: Lozanoc is not recommended for use in children and elderly patients.
Drug Interactions
Lozanoc interacts with many medications. Some must not be taken together, while others may require dose adjustments. Always tell your doctor about all medications you’re taking.
Wait period required: Wait at least 2 weeks after stopping Lozanoc before taking certain prohibited medications.
- Allergy medications (terfenadine, astemizole, mizolastine)
- Heart medications (bepridil, felodipine, nisoldipine, lercanidipine, ranolazine, eplerenone, ivabradine)
- Blood thinners (apixaban, rivaroxaban, dabigatran, edoxaban, vorapaxar, warfarin)
- Gastric medications (cisapride, domperidone)
- Pain medications (levomethadyl, methadone, alfentanil, buprenorphine, oxycodone, sufentanil, fentanyl)
- Psychiatric medications (pimozide, lurasidone, sertindole, alprazolam, aripiprazole, haloperidol, midazolam)
- Cholesterol medications (simvastatin, lomitapide, lovastatin, atorvastatin)
- Heart rhythm medications (dronedarone, dofetilide, quinidine, disopyramide)
- Migraine medications (dihydroergotamine, ergotamine, eletriptan)
- Cancer medications (multiple antineoplastics listed)
- HIV/AIDS medications (multiple antiretrovirals listed)
- Hepatitis C medications (multiple antivirals listed)
- Tuberculosis medications (bedaquiline, delamanid, rifampicin, rifabutin, isoniazid)
- Antibiotics (ciprofloxacin, erythromycin, clarithromycin, telithromycin)
- Seizure medications (phenytoin, phenobarbital, carbamazepine)
- Diabetes medications (repaglinide, saxagliptin)
- Stomach acid reducers (antacids, H2 antagonists, proton pump inhibitors)
Alcohol & Driving
Lozanoc may cause dizziness in some people, which can affect your ability to drive or operate machinery safely.
Alcohol
No specific alcohol warnings mentioned in the source material.
Driving and Operating Machinery
Be careful before driving or using machines until you know how Lozanoc affects you. Lozanoc may cause dizziness. If you experience dizziness or similar effects, avoid driving and using machines. Make sure you know how you react to Lozanoc before engaging in potentially dangerous activities.
Temperature Regulation
No specific temperature regulation warnings mentioned in the source material.
Storage
Keep Lozanoc capsules in their original pack until it’s time to take them. Store below 25°C in a cool, dry place away from moisture, heat, or sunlight. Do not store in the bathroom, near a sink, in the car, or on windowsills. Keep out of reach of children.
Overdose Information
If you think you have taken too much Lozanoc, seek urgent medical attention immediately. Phone the Poisons Information Centre (13 11 26), contact your doctor, or go to the Emergency Department at your nearest hospital, even if you have no symptoms of discomfort or poisoning.
Frequently Asked Questions
Don’t worry if you don’t see immediate improvement. With skin infections, marks typically disappear a few weeks after finishing treatment as new skin grows. With nail infections, marks may take 6-9 months to disappear because new nail needs to grow.
Yes, Lozanoc can be taken before or after a meal.
If it’s almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take a double dose to make up for the missed one. Take Lozanoc regularly at the same time each day.
No, always complete the full treatment as directed by your doctor, even if the signs of infection have gone. This ensures the infection is fully treated.
No, DO NOT SUBSTITUTE Lozanoc with other brands of itraconazole as they are not interchangeable. Lozanoc has higher absorption than other itraconazole capsules and requires different dosing.
Call your doctor straight away if you become pregnant while taking Lozanoc. The medication should not be taken during pregnancy.
Lozanoc is not recommended for use in elderly patients.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.