Lomotil (Diphenoxylate Hydrochloride And Atropine Sulfate Monohydrate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
Diphenoxylate hydrochloride and atropine sulfate monohydrate
Drug Class
Anti-diarrhoeal
Used For
Treatment of acute or chronic diarrhoea
How Taken
Oral tablets, typically 2 tablets three to four times daily

What Is Lomotil Used For?

Lomotil is an anti-diarrhoeal medication that helps reduce the frequency of bowel movements.

Primary Uses

Lomotil is primarily used to treat both short-term and long-term episodes of diarrhoea.

How It Works

The active ingredient diphenoxylate slows down intestinal movement, while atropine is included to deter misuse.

Good to know: Lomotil is not considered addictive when taken as prescribed.

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How to Take Lomotil

Follow your doctor's instructions on how to take Lomotil for effective management of diarrhoea.

Dosage Instructions

The usual starting dose is 2 tablets taken three to four times a day, not exceeding 8 tablets in 24 hours.

What If You Miss a Dose?

If you miss a dose, skip it and take your next dose at the scheduled time. Do not double up.

Important: Never exceed the recommended dosage to avoid serious side effects.

Available Tablet Strengths

5mg
5mg Tablet White, Round • LT
10mg
10mg Tablet White, Round • LT
15mg
15mg Tablet White, Round • LT
20mg
20mg Tablet White, Round • LT
30mg
30mg Tablet White, Round • LT

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Nausea
  • Vomiting
  • Stomach upset
  • Drowsiness
  • Dizziness

Seek immediate medical attention if you experience:

  • Severe allergic reactions
  • Severe stomach or bowel problems
  • Fast shallow breathing
  • Rapid heartbeat
  • High fever

Impulse Control Issues

High doses may lead to potential abuse and impulse control problems.

Important Warnings

Be aware of potential risks and contraindications before using Lomotil.

Who Should Not Take Lomotil

Do not use Lomotil if you are allergic to diphenoxylate or atropine, have jaundice, or suffer from certain bowel conditions.

Medical Conditions to Discuss

Inform your doctor if you have liver disease, kidney disease, or a history of drug abuse.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as Lomotil may affect newborns.

Elderly Patients With Dementia: Caution is advised for elderly patients, particularly those with dementia.

Drug Interactions

Certain medications may interact with Lomotil, affecting its efficacy.

  • Tranquillisers
  • Barbiturates
  • Antidepressants (e.g., MAOIs)

Alcohol & Driving

Exercise caution when consuming alcohol or operating machinery while taking Lomotil.

Alcohol

Avoid alcohol as it may enhance the effects of Lomotil.

Driving and Operating Machinery

Be aware that Lomotil can cause drowsiness or dizziness, affecting your ability to drive.

Storage

Store Lomotil below 30°C in a cool, dry place away from moisture and sunlight, out of reach of children.

Overdose Information

In case of overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

Lomotil typically begins to work within a few hours to reduce diarrhoea.

Lomotil can be taken with or without food, but it's advisable to follow your doctor's instructions.

Lomotil is not considered addictive when used as prescribed, but misuse can lead to dependency.

Consult your doctor before stopping Lomotil, especially if you have been using it for a long time.

It is recommended to avoid alcohol while taking Lomotil due to potential increased effects.

Weight gain is not a common side effect of Lomotil.

Elderly patients should use Lomotil with caution, particularly those with dementia.

If you miss a dose, skip it and take your next dose at the scheduled time; do not double up.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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