Lofenoxal (Diphenoxylate Hydrochloride And Atropine Sulfate Monohydrate)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Lofenoxal Used For?
Lofenoxal is an anti-diarrhoeal medication that helps manage episodes of diarrhoea by slowing down intestinal movements.
Primary Uses
It is used for both short-term and long-term treatment of diarrhoea.
How It Works
Diphenoxylate acts to reduce diarrhoea by decreasing the speed of intestinal movement, while atropine is included to deter misuse.
Good to know: Lofenoxal is not considered addictive when used as directed.
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How to Take Lofenoxal
Follow your doctor's instructions on how to take Lofenoxal for effective management of diarrhoea.
Dosage Instructions
The typical starting dose is 2 tablets taken three to four times a day, not exceeding 8 tablets in a 24-hour period.
What If You Miss a Dose?
If you miss a dose and it's close to your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not double up.
Important: Never exceed the recommended dosage to avoid potential overdose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Nausea
- Vomiting
- Stomach upset
- Drowsiness
- Dizziness
Seek immediate medical attention if you experience:
- Severe allergic reactions
- Severe stomach or bowel problems
- Fast shallow breathing
- Fast heartbeat
- Very high temperature
Impulse Control Issues
There is a potential risk of abuse with Lofenoxal due to its effects.
Important Warnings
Be aware of the following warnings before using Lofenoxal.
Who Should Not Take Lofenoxal
Do not use Lofenoxal if you are allergic to diphenoxylate or atropine, have jaundice, or suffer from certain gastrointestinal infections or inflammatory bowel diseases.
Medical Conditions to Discuss
Consult your doctor if you have liver disease, kidney disease, Down's Syndrome, or a history of drug abuse.
Pregnancy and Breastfeeding
Lofenoxal should not be taken during labor as it may affect newborns. Discuss with your doctor if you are pregnant or breastfeeding.
Elderly Patients With Dementia: Caution is advised when prescribing Lofenoxal to elderly patients, especially those with dementia.
Drug Interactions
Lofenoxal may interact with other medications, affecting its efficacy.
- Tranquillisers
- Barbiturates
- Antidepressants (including MAOIs)
Alcohol & Driving
Be cautious with alcohol and operating machinery while taking Lofenoxal.
Alcohol
Avoid consuming alcohol while using Lofenoxal, as it may enhance the medication's effects.
Driving and Operating Machinery
Be aware that Lofenoxal may cause drowsiness or dizziness, which can impair your ability to drive or operate machinery safely.
Storage
Store Lofenoxal below 30°C in a cool, dry place away from moisture, heat, and sunlight. Keep out of reach of children.
Overdose Information
In case of overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital, even if no symptoms are present.
Frequently Asked Questions
Lofenoxal typically starts to work within a few hours to help control diarrhoea.
You can take Lofenoxal with or without food, but it is advisable to follow your doctor's instructions.
Lofenoxal is not considered addictive when used as directed, but misuse can lead to dependency.
Consult your doctor before stopping Lofenoxal, especially if you have been taking it for a long time.
It is advised to avoid alcohol while taking Lofenoxal, as it may enhance side effects.
Weight gain is not a commonly reported side effect of Lofenoxal.
Elderly patients should use Lofenoxal with caution, especially those with dementia.
If you miss a dose, skip it and take your next dose at the scheduled time. Do not double the dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.