Leqvio (Inclisiran)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
inclisiran
Drug Class
cholesterol-lowering medication
Used For
Lowering LDL-cholesterol ('bad' cholesterol) in adults with high cholesterol levels
How Taken
Injection under the skin, initially one dose, then at 3 months, followed by every 6 months

What Is Leqvio Used For?

Leqvio is a medication that helps reduce levels of LDL-cholesterol, which can lead to heart disease and circulation issues. It is used alongside a cholesterol-lowering diet and exercise.

Primary Uses

Leqvio is primarily used to treat adults with high LDL-cholesterol levels, those with heart disease, or individuals at increased risk of heart attacks.

How It Works

Leqvio works by silencing the gene for a protein called PCSK9, which helps lower 'bad' cholesterol levels.

Good to know: Leqvio is not addictive.

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How to Take Leqvio

Leqvio is administered as an injection by a healthcare professional. It is important to follow your doctor's instructions and maintain a healthy lifestyle.

Dosage Instructions

The recommended dosage is one injection initially, followed by another at 3 months, and then every 6 months.

What If You Miss a Dose?

If you miss an appointment for your injection, contact your healthcare provider as soon as possible to reschedule.

Important: Do not double your dose if you miss an appointment.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Injection site reactions such as pain, redness, or rash

Important Warnings

It's crucial to be aware of specific warnings before using Leqvio.

Who Should Not Take Leqvio

Do not use Leqvio if you are allergic to inclisiran or any of its ingredients.

Medical Conditions to Discuss

Consult your doctor if you have other medical conditions or are taking other medications.

Pregnancy and Breastfeeding

The effects of Leqvio during pregnancy are unknown. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Drug Interactions

Leqvio is not expected to interact with other medications, although it has not been extensively tested.

Alcohol & Driving

Leqvio is not expected to impair your ability to drive or operate machinery.

Alcohol

There are no known interactions between Leqvio and alcohol.

Driving and Operating Machinery

Leqvio should not affect your ability to drive or use machines.

Storage

Store Leqvio below 30°C and do not freeze.

Overdose Information

If you suspect an overdose of Leqvio, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

Leqvio is administered as an injection and is designed to lower LDL-cholesterol levels over time, with follow-up doses every 6 months.

There are no specific dietary restrictions mentioned for Leqvio, but it is important to maintain a cholesterol-lowering diet.

No, Leqvio is not considered addictive.

Consult your doctor before stopping Leqvio, as it is important to manage cholesterol levels effectively.

Yes, there are no known interactions between Leqvio and alcohol.

There is no information provided regarding weight gain associated with Leqvio.

Consult your doctor to determine if Leqvio is appropriate for elderly patients, especially those with other health conditions.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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