Kliogest (Estradiol (As Hemihydrate) And Norethisterone Acetate)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Kliogest Used For?
Kliogest is a hormone replacement therapy that helps alleviate symptoms associated with menopause and aids in preventing the loss of bone density after menopause.
Primary Uses
Kliogest is primarily used to relieve menopausal symptoms and to prevent osteoporosis due to menopause.
How It Works
Kliogest contains estradiol, an estrogen, and norethisterone acetate, a progestogen, which work together to balance hormone levels in the body.
Good to know: Kliogest is not considered addictive.
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How to Take Kliogest
Kliogest should be taken daily at the same time to maintain consistent hormone levels.
Dosage Instructions
Take one tablet daily for 28 days. After finishing a pack, start a new one without interruption.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's been more than 12 hours, skip the missed dose and continue with your next scheduled dose.
Important: Do not take a double dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Breast tenderness or pain
- Irregular periods
- Nausea
- Headaches
- Mood changes
Seek immediate medical attention if you experience:
- Signs of a blood clot (chest pain, difficulty breathing)
- Severe allergic reactions
- Unexplained migraines
- Changes in vision
- Jaundice
Important Warnings
There are several important safety considerations to keep in mind when using Kliogest.
Who Should Not Take Kliogest
Do not use Kliogest if you have a history of breast cancer, uterine cancer, unexplained vaginal bleeding, blood clots, liver disease, or if you are pregnant or breastfeeding.
Medical Conditions to Discuss
Discuss with your doctor if you have conditions such as fibroids, diabetes, high blood pressure, or a history of blood clots.
Pregnancy and Breastfeeding
Kliogest should not be taken if you are pregnant, suspect you may be pregnant, or are breastfeeding.
Elderly Patients With Dementia: There is a risk of increased memory loss in women who start HRT after the age of 65.
Drug Interactions
Certain medications may affect how Kliogest works or may be affected by it.
- Other estrogen-containing medications
- Anti-infectives like ketoconazole
- Barbiturates
- Epilepsy medications such as phenytoin and carbamazepine
- Some antibiotics like rifampicin
- St John's Wort
- Corticosteroids
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Kliogest.
Alcohol
There is no specific information on the effects of alcohol while taking Kliogest.
Driving and Operating Machinery
No specific information is available regarding driving or operating machinery while on Kliogest.
Storage
Store Kliogest in a cool, dry place below 25°C, away from moisture and sunlight.
Overdose Information
In case of overdose, seek medical attention immediately. Contact the Poisons Information Centre at 13 11 26 or visit the nearest hospital.
Frequently Asked Questions
Kliogest typically starts to relieve menopausal symptoms within a few weeks of starting treatment.
Kliogest can be taken with or without food.
No, Kliogest is not considered addictive.
Do not stop taking Kliogest suddenly without consulting your doctor, as this may lead to withdrawal symptoms.
There is no specific information on the effects of alcohol while taking Kliogest, but moderation is advised.
Weight changes can occur, but it varies by individual; consult your doctor if you have concerns.
Elderly patients should discuss their health history with their doctor to assess the risks before taking Kliogest.
If you miss a dose, take it as soon as you remember unless it's been more than 12 hours.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.