Jadenu (Deferasirox)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Jadenu Used For?
Jadenu is an iron chelator that helps remove excess iron from the body, which can accumulate due to blood transfusions or certain medical conditions.
Primary Uses
It is used for treating iron overload in patients aged 6 years and older due to repeated blood transfusions, in patients aged 2 to 5 years unable to take desferrioxamine, and in patients aged 10 years and older with thalassemia syndromes who are not transfusion dependent.
How It Works
Jadenu binds to excess iron in the body, facilitating its removal since the body lacks a natural mechanism to eliminate excess iron.
Good to know: Jadenu is not addictive.
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How to Take Jadenu
Take Jadenu as directed by your doctor, either on an empty stomach or with a light meal.
Dosage Instructions
The typical starting dose is 14 mg per kilogram of body weight for patients receiving regular blood transfusions and 7 mg per kilogram for those not receiving transfusions. Your doctor will determine the exact dosage based on your needs.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
Important: Never double the dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- nausea
- vomiting
- diarrhea
- abdominal pain
- headache
- rash
Seek immediate medical attention if you experience:
- shortness of breath
- wheezing
- swelling of the face or throat
- severe skin rash
- vomiting blood
- severe abdominal pain
- blurred vision
- yellowing of skin or eyes
Important Warnings
Be aware of the following warnings before using Jadenu.
Who Should Not Take Jadenu
Do not use Jadenu if you are allergic to deferasirox or any of its ingredients, have severe kidney problems, low platelet counts, or advanced myelodysplastic syndrome (MDS) or other cancers where chelation treatment is not expected to help.
Medical Conditions to Discuss
Inform your doctor if you have allergies, kidney or liver issues, abnormal blood test results, or a history of stomach ulcers.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding to discuss the potential risks and benefits.
Drug Interactions
Certain medications can interact with Jadenu, affecting its efficacy.
- ciclosporin
- midazolam
- simvastatin
- hormonal contraceptives
- aspirin
- ibuprofen
- oral bisphosphonates
- anticoagulants
- antacids containing aluminum
- repaglinide
- phenytoin
- phenobarbital
- ritonavir
- rifampicin
- paclitaxel
- cholestyramine
- theophylline
- busulfan
Alcohol & Driving
Be cautious when consuming alcohol and operating vehicles or machinery while taking Jadenu.
Alcohol
Consult your doctor about alcohol consumption while on this medication.
Driving and Operating Machinery
Jadenu may cause dizziness; avoid driving or using machinery until you know how it affects you.
Storage
Store Jadenu in its original container in a cool, dry place below 30°C, away from moisture and sunlight. Keep out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention by contacting your doctor or going to the nearest emergency department.
Frequently Asked Questions
The time it takes for Jadenu to work can vary by individual, but it is important to follow your doctor's instructions for optimal results.
You can take Jadenu on an empty stomach or with a light meal, but avoid high-fat meals.
No, Jadenu is not considered addictive.
Do not stop taking Jadenu abruptly without consulting your doctor, as it may affect your treatment.
Consult your doctor regarding alcohol consumption while on Jadenu.
Weight gain is not commonly associated with Jadenu; however, discuss any concerns with your doctor.
Elderly patients should discuss their health conditions with their doctor to ensure Jadenu is safe for them.
If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.