Itovebi (Inavolisib)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Itovebi Used For?
Itovebi is an anti-cancer medication that contains inavolisib, used primarily for treating a specific type of breast cancer.
Primary Uses
Itovebi is prescribed for adults with hormone receptor-positive, HER2-negative breast cancer that has spread to nearby tissues or lymph nodes after surgery, or has metastasized to other parts of the body. It is used in conjunction with endocrine therapy and is effective in patients with a PIK3CA gene mutation.
How It Works
Itovebi works by inhibiting the action of the p110 alpha protein, which is produced by the PIK3CA gene. This gene is often mutated in cancer, leading to uncontrolled growth of cancer cells. By blocking this protein, Itovebi helps slow down or stop the growth and spread of cancer.
Good to know: Itovebi is not addictive.
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How to Take Itovebi
Itovebi should be taken as directed by your healthcare provider.
Dosage Instructions
The typical dosage of Itovebi is 9 mg taken once daily. It can be taken with or without food.
What If You Miss a Dose?
If you miss a dose, you can take it up to 9 hours late. If more than 9 hours have passed, skip the missed dose and resume your regular schedule the next day. Do not take a double dose.
Important: Never take a double dose of Itovebi.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- stomach pain
- nausea
- vomiting
- disturbed sense of taste
- dry eyes
- skin rash
- dry skin
- unusual bruising or bleeding
- painful urination
- tiredness
- headache
- loss of appetite
- weight loss
- hair thinning
Seek immediate medical attention if you experience:
- high blood sugar levels (hyperglycaemia)
- inflammation of the lining of the mouth (stomatitis)
- diarrhoea
Important Warnings
There are several important considerations to keep in mind while using Itovebi.
Who Should Not Take Itovebi
Do not use Itovebi if you are allergic to inavolisib or any of its ingredients.
Medical Conditions to Discuss
Inform your doctor if you have a history of diabetes or high blood sugar, as well as any other medical conditions or medications you are taking.
Pregnancy and Breastfeeding
Itovebi can harm an unborn baby. Women who can become pregnant should use effective non-hormonal birth control during treatment and for 2 weeks after the last dose. It is not known if Itovebi passes into breast milk, so breastfeeding is not recommended during treatment.
Elderly Patients With Dementia: No specific warnings for elderly patients with dementia were mentioned.
Drug Interactions
Certain medications may interact with Itovebi and affect its effectiveness.
Alcohol & Driving
Be cautious with alcohol consumption and operating vehicles or machinery while taking Itovebi.
Alcohol
Avoid alcohol as it may worsen side effects.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Itovebi affects you.
Storage
Store Itovebi at room temperature, below 30°C, in a cool, dry place away from moisture and heat. Keep it out of reach of children.
Overdose Information
If you suspect an overdose of Itovebi, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26, or go to the nearest emergency department.
Frequently Asked Questions
The time it takes for Itovebi to show effects can vary by individual; consult your doctor for specific information.
Yes, Itovebi can be taken with or without food.
No, Itovebi is not considered addictive.
Do not stop taking Itovebi without consulting your doctor, as this may affect your treatment.
It is advisable to avoid alcohol while taking Itovebi due to potential interactions.
Weight loss is a common side effect, but individual responses may vary.
Yes, elderly patients can take Itovebi at the same dosage as other adults, but should discuss any concerns with their doctor.
If you miss a dose, take it within 9 hours. If more than 9 hours have passed, skip the missed dose and continue with your next dose as scheduled.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.