Isoptin (Verapamil Hydrochloride)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
verapamil hydrochloride
Drug Class
calcium channel blockers
Used For
high blood pressure, angina, irregular heartbeats
How Taken
oral tablets taken two to three times a day; ISOPTIN SR taken once or twice daily

What Is Isoptin Used For?

Isoptin is a medication that helps manage conditions related to the heart and blood pressure.

Primary Uses

Isoptin is primarily used to treat high blood pressure (hypertension), angina (chest pain), and irregular heartbeats (arrhythmias).

How It Works

Isoptin works by relaxing blood vessels, allowing more blood and oxygen to reach the heart, while also lowering blood pressure.

Good to know: Isoptin is not considered addictive.

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How to Take Isoptin

Follow your doctor's instructions on how to take Isoptin for optimal results.

Dosage Instructions

Isoptin tablets are typically taken two to three times a day, while ISOPTIN SR is usually taken once daily or sometimes twice daily.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up on doses.

Important: Never take a double dose to make up for a missed one.

Available Tablet Strengths

40mg
40mg Tablet White, Biconvex • Isoptin 40
80mg
80mg Tablet White, Biconvex • Isoptin 80
180mg
180mg Tablet Old rose, Oval • SR 180
240mg
240mg Tablet Light green, Oblong • SR 240

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • constipation
  • dizziness
  • light-headedness
  • nausea
  • upset stomach
  • headache
  • tiredness
  • flushing

Seek immediate medical attention if you experience:

  • chest pain
  • fainting
  • irregular heartbeat
  • shortness of breath
  • swelling of feet and legs
  • fever
  • upper stomach pain
  • feeling generally unwell
  • severe blisters
  • skin rash
  • itching
  • flaking skin

Important Warnings

Be aware of the following warnings before using Isoptin.

Who Should Not Take Isoptin

Do not use Isoptin if you are allergic to verapamil hydrochloride or any of its ingredients, have certain heart conditions, low blood pressure, or are taking specific medications like ivabradine.

Medical Conditions to Discuss

Discuss with your doctor if you have heart problems, circulatory diseases, liver or kidney issues, or neuromuscular conditions.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as Isoptin may affect your baby.

Elderly Patients With Dementia: Elderly patients may have an increased risk of side effects.

Drug Interactions

Certain medications may interact with Isoptin and affect its effectiveness.

Grapefruit interaction: Avoid grapefruit and its juice as they may increase the blood levels of verapamil.

  • Beta-blockers (e.g., atenolol, propranolol)
  • Ivabradine
  • Digoxin
  • Quinidine, flecainide, amiodarone, disopyramide
  • Prazosin, terazosin
  • Statins (e.g., atorvastatin, simvastatin)
  • Direct Oral Anticoagulants (e.g., dabigatran)
  • Aspirin
  • Colchicine, sulfinpyrazone
  • St John's Wort, imipramine, buspirone, midazolam, lithium
  • Phenytoin, carbamazepine, phenobarbital
  • Cyclosporin, everolimus, sirolimus, tacrolimus
  • Erythromycin, clarithromycin, telithromycin, rifampicin
  • Ritonavir
  • General anaesthetics
  • Muscle relaxants
  • Theophylline
  • Doxorubicin
  • Cimetidine
  • Metformin, glibenclamide

Alcohol & Driving

It's important to be cautious with alcohol and while driving when taking Isoptin.

Alcohol

Avoid alcohol while taking Isoptin, as it may worsen dizziness or light-headedness.

Driving and Operating Machinery

Be careful when driving or operating machinery until you know how Isoptin affects you, as it may cause dizziness or tiredness.

Storage

Store Isoptin below 25°C in a cool, dry place, away from moisture and heat. Keep out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Symptoms may include difficulty breathing, slow heartbeat, chest pain, or fainting.

Frequently Asked Questions

Isoptin usually starts to work within a few hours, but full effects may take longer.

Isoptin SR should be taken with food, while Isoptin tablets can be taken with or without food.

No, Isoptin is not considered addictive.

Do not stop taking Isoptin without consulting your doctor, as it may worsen your condition.

It is advised to avoid alcohol while taking Isoptin, as it may increase dizziness.

Weight gain is not commonly associated with Isoptin.

Elderly patients may have a higher risk of side effects and should be monitored closely.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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