Invega Trinza (Paliperidone Palmitate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
paliperidone palmitate
Drug Class
antipsychotic agents
Used For
treatment of schizophrenia in adults
How Taken
injection into the muscle every 3 months

What Is Invega Trinza Used For?

Invega Trinza is an injectable medication used primarily for treating schizophrenia in adults. It helps manage symptoms associated with this mental illness.

Primary Uses

Invega Trinza is used to treat schizophrenia, which includes symptoms such as hallucinations, delusions, paranoia, and social withdrawal.

How It Works

Invega Trinza works by correcting chemical imbalances in the brain that contribute to the symptoms of schizophrenia.

Good to know: Invega Trinza is not considered addictive.

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How to Take Invega Trinza

Invega Trinza is administered as an injection by a healthcare professional. It is important to follow your doctor's instructions regarding the timing and dosage.

Dosage Instructions

The initial treatment with Invega Trinza should not begin until you have tolerated Invega Sustenna for at least 4 months. After the first dose, it is typically administered once every 3 months.

What If You Miss a Dose?

If you miss an appointment for your injection, contact your doctor as soon as possible to reschedule.

Important: Do not double the dose if you miss an injection.

Available Tablet Strengths

175 mg
175 mg Tablet White to off-white, Suspension • Aust R 261332
263 mg
263 mg Tablet White to off-white, Suspension • Aust R 261406
350 mg
350 mg Tablet White to off-white, Suspension • Aust R 261407
525 mg
525 mg Tablet White to off-white, Suspension • Aust R 261408

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • difficulty falling or staying asleep
  • drowsiness
  • headache
  • muscle weakness
  • pain at the injection site
  • irritability
  • weight gain

Seek immediate medical attention if you experience:

  • serious allergic reactions
  • heart or blood pressure problems
  • high blood sugar or diabetes
  • severe skin reactions
  • sudden weakness or numbness
  • involuntary movements (tardive dyskinesia)
  • neuroleptic malignant syndrome

Impulse Control Issues

Invega Trinza may cause impulse control problems, including issues related to gambling or spending.

Important Warnings

There are several important warnings to consider before using Invega Trinza.

Who Should Not Take Invega Trinza

Do not use Invega Trinza if you have had an allergic reaction to paliperidone or risperidone, or any of its ingredients.

Medical Conditions to Discuss

Discuss any history of heart problems, diabetes, kidney or liver issues, seizures, or any other medical conditions with your doctor before starting treatment.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as Invega Trinza may pose risks to the newborn.

Elderly Patients With Dementia: Elderly patients with dementia may have an increased risk of stroke or death when taking Invega Trinza.

Drug Interactions

Certain medications may interact with Invega Trinza and affect its efficacy.

Grapefruit interaction: Avoid grapefruit as it may affect how Invega Trinza works.

  • sleeping tablets
  • tranquillisers
  • painkillers
  • antihistamines
  • medicines for epilepsy or Parkinson's disease
  • medicines for depression or anxiety
  • medicines for heart rhythm issues
  • medicines for high blood pressure

Alcohol & Driving

Be cautious with alcohol and operating vehicles or machinery while taking Invega Trinza.

Alcohol

Avoid alcohol as it can enhance the effects of Invega Trinza.

Driving and Operating Machinery

Know how Invega Trinza affects you before driving or using machinery, as it may cause dizziness.

Temperature Regulation

Invega Trinza may affect your body's ability to regulate temperature.

Storage

Invega Trinza should be stored by your healthcare provider. If you need to store it at home, keep it in a cool, dry place below 25°C and protected from light.

Overdose Information

If you suspect an overdose of Invega Trinza, seek immediate medical attention. Contact your doctor or go to the nearest emergency department.

Frequently Asked Questions

It may take some time for symptoms of schizophrenia to improve after starting Invega Trinza.

There are no specific dietary restrictions mentioned, but consult your doctor for personalized advice.

No, Invega Trinza is not considered addictive.

Do not stop taking Invega Trinza suddenly without consulting your doctor, as it may worsen your condition.

It is advised to avoid alcohol while using Invega Trinza.

Weight gain is a possible side effect of Invega Trinza, so monitoring your weight is important.

Elderly patients with dementia may have an increased risk of stroke or death when taking Invega Trinza.

Contact your doctor as soon as possible to reschedule your missed injection.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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