Invega Sustenna (Paliperidone Palmitate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
paliperidone palmitate
Drug Class
antipsychotic agents
Used For
treating schizophrenia in adults
How Taken
injection administered by a healthcare professional, typically once a month

What Is Invega Sustenna Used For?

Invega Sustenna is a medication that helps manage symptoms of schizophrenia, a mental illness characterized by disturbances in thought, feelings, and behavior.

Primary Uses

It is primarily used to treat schizophrenia in adults, helping to alleviate symptoms such as hallucinations, delusions, and paranoia.

How It Works

Invega Sustenna works by correcting chemical imbalances in the brain associated with schizophrenia.

Good to know: Invega Sustenna is not considered addictive.

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How to Take Invega Sustenna

Invega Sustenna is administered through an injection by a healthcare professional, ensuring proper dosage and monitoring.

Dosage Instructions

The initial dose is typically 150 mg, followed by a second dose of 100 mg one week later. The usual monthly maintenance dose is 75 mg, but it can range from 25 mg to 150 mg based on individual needs and kidney function.

What If You Miss a Dose?

If you miss an appointment for your injection, contact your doctor as soon as possible for guidance on what to do next.

Important: Never double the dose if you miss an injection; always consult your doctor.

Available Tablet Strengths

25 mg
25 mg Tablet White to off-white, Suspension • Aust R 160858
50 mg
50 mg Tablet White to off-white, Suspension • Aust R 160856
75 mg
75 mg Tablet White to off-white, Suspension • Aust R 160859
100 mg
100 mg Tablet White to off-white, Suspension • Aust R 160860
150 mg
150 mg Tablet White to off-white, Suspension • Aust R 160857

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Difficulty falling or staying asleep
  • Headache
  • Drowsiness
  • Tiredness
  • Injection site pain

Seek immediate medical attention if you experience:

  • Severe allergic reactions
  • Heart or blood pressure issues
  • High blood sugar or diabetes
  • Severe skin reactions
  • Symptoms of mini-strokes
  • Tardive dyskinesia
  • Neuroleptic malignant syndrome

Impulse Control Issues

Invega Sustenna may lead to impulse control problems, including issues with gambling or spending.

Important Warnings

It's crucial to understand the potential risks and contraindications associated with Invega Sustenna.

Who Should Not Take Invega Sustenna

Do not use Invega Sustenna if you are allergic to paliperidone, risperidone, or any of its ingredients.

Medical Conditions to Discuss

Discuss any history of neuroleptic malignant syndrome, tardive dyskinesia, heart problems, kidney or liver issues, diabetes, or a history of blood clots with your doctor.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as Invega Sustenna may pose risks to newborns.

Elderly Patients With Dementia: Elderly patients with dementia may have an increased risk of stroke or death when treated with antipsychotic medications.

Drug Interactions

Certain medications can interact with Invega Sustenna, affecting its efficacy.

Grapefruit interaction: Avoid grapefruit as it may affect how Invega Sustenna works.

  • Sleeping tablets
  • Tranquillisers
  • Painkillers
  • Antihistamines
  • Epilepsy medications
  • Parkinson's disease medications
  • High blood pressure medications
  • Heart rhythm medications
  • Depression and anxiety medications
  • Psychostimulants
  • Nausea or vomiting medications

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while on Invega Sustenna.

Alcohol

Avoid alcohol as it can enhance the effects of Invega Sustenna.

Driving and Operating Machinery

Assess how Invega Sustenna affects you before driving or using machinery, as it may cause dizziness or drowsiness.

Temperature Regulation

Monitor your body temperature, as Invega Sustenna may affect your ability to regulate it.

Storage

Invega Sustenna should be stored by your healthcare provider. If you must store it at home, keep it in a cool, dry place away from light, below 25°C, and do not use it past the expiration date.

Overdose Information

In the rare event of an overdose, symptoms may include drowsiness, low blood pressure, and abnormal heart rhythms. Seek immediate medical attention if you suspect an overdose.

Frequently Asked Questions

It may take some time for symptoms to improve after starting Invega Sustenna.

There are no specific dietary restrictions mentioned for Invega Sustenna.

Invega Sustenna is not considered addictive.

Consult your doctor before stopping Invega Sustenna to avoid withdrawal symptoms.

It is advised to avoid alcohol while using Invega Sustenna.

There is a possibility of weight gain when taking Invega Sustenna, so monitoring your weight is important.

Elderly patients with dementia may have an increased risk of stroke or death when treated with antipsychotic medications.

Contact your doctor as soon as possible if you miss an appointment for your injection.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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