Imfinzi (Durvalumab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Imfinzi Used For?
Imfinzi is a medication that helps treat several types of cancers by enhancing the immune system's ability to fight cancer cells.
Primary Uses
Imfinzi is primarily used for non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), biliary tract cancer (BTC), unresectable hepatocellular carcinoma (uHCC), endometrial cancer, and muscle-invasive bladder cancer (MIBC).
How It Works
Imfinzi works by blocking certain proteins that prevent the immune system from attacking cancer cells, thereby helping to destroy them.
Good to know: Imfinzi is not considered addictive.
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How to Take Imfinzi
Imfinzi is given as an infusion by a healthcare professional, and the treatment schedule will be determined by your doctor.
Dosage Instructions
The infusion typically lasts about 1 hour and is administered every 2, 3, or 4 weeks, depending on the type of cancer and whether it is given with other treatments.
What If You Miss a Dose?
If you miss an appointment for your infusion, contact your doctor immediately to reschedule.
Important: Do not miss a dose of Imfinzi.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- cough
- diarrhea
- stomach pain
- skin rash or itchiness
- fever
- swelling of the legs
- upper respiratory tract infection
- underactive thyroid gland (hypothyroidism)
- overactive thyroid gland
Seek immediate medical attention if you experience:
- lung inflammation
- liver inflammation
- intestinal inflammation
- problems with hormone glands
- kidney inflammation
- urinary tract infection
- skin or mouth inflammation
- heart inflammation
- muscle inflammation
- blood issues
- infusion-related reactions
- encephalitis or meningitis
- Guillain-Barré syndrome
- eye inflammation
Important Warnings
There are several important considerations to keep in mind before using Imfinzi.
Who Should Not Take Imfinzi
Do not use Imfinzi if you are allergic to durvalumab or any of its ingredients.
Medical Conditions to Discuss
Discuss any history of autoimmune diseases, organ transplants, lung or breathing problems, liver issues, or any other medical conditions with your doctor.
Pregnancy and Breastfeeding
Imfinzi should not be used during pregnancy as it may harm the developing baby. Effective birth control is recommended during treatment and for at least 3 months after the last dose. It is also not recommended for breastfeeding mothers.
Drug Interactions
Some medications may affect how Imfinzi works.
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while on Imfinzi.
Alcohol
Consult your doctor regarding alcohol consumption while taking Imfinzi.
Driving and Operating Machinery
Be careful when driving or using machinery until you know how Imfinzi affects you.
Storage
Store unopened vials of Imfinzi in the refrigerator at 2°C to 8°C, protected from light. Do not freeze or shake.
Overdose Information
If an overdose occurs, seek immediate medical attention.
Frequently Asked Questions
The time it takes for Imfinzi to work can vary based on the individual and the type of cancer being treated.
Imfinzi is administered as an infusion, so food intake does not directly affect its administration.
No, Imfinzi is not considered addictive.
Consult your doctor before stopping Imfinzi, as they will provide guidance based on your treatment plan.
It's best to consult your doctor regarding alcohol consumption while on Imfinzi.
Weight changes can occur, and any concerns should be discussed with your doctor.
Elderly patients should discuss their health conditions with their doctor to determine if Imfinzi is suitable for them.
If you miss a dose, contact your doctor immediately to reschedule your appointment.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.