Glyxambi (Empagliflozin And Linagliptin)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
empagliflozin and linagliptin
Drug Class
SGLT2 inhibitors and DPP-4 inhibitors
Used For
Lowering blood sugar levels in type 2 diabetes mellitus
How Taken
Oral tablet once daily

What Is Glyxambi Used For?

Glyxambi is a medication that helps manage blood sugar levels in individuals with type 2 diabetes mellitus. It is typically used when diet and exercise alone are not sufficient.

Primary Uses

Glyxambi is primarily used to treat type 2 diabetes mellitus, especially when other diabetes medications, like metformin, do not adequately control blood sugar.

How It Works

Glyxambi combines empagliflozin, which increases glucose excretion through urine, and linagliptin, which enhances insulin production, to effectively lower blood sugar levels.

Good to know: Glyxambi is not considered addictive.

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How to Take Glyxambi

Follow your doctor's instructions on how to take Glyxambi. It is usually taken once daily.

Dosage Instructions

The standard dosage is one tablet daily, either Glyxambi 10 mg/5 mg or Glyxambi 25 mg/5 mg, as prescribed by your doctor.

What If You Miss a Dose?

If you miss a dose and it's less than 12 hours until your next scheduled dose, skip the missed dose. If more than 12 hours have passed, take it as soon as you remember but do not double up on doses.

Important: Never take a double dose to make up for a missed one.

Available Tablet Strengths

10mg/5mg
10mg/5mg Tablet Pale yellow, Arc triangular • 10/5
25mg/5mg
25mg/5mg Tablet Pale pink, Arc triangular • 25/5

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Constipation
  • Cough
  • Swelling of the nose or throat
  • Mouth ulceration
  • Itching

Seek immediate medical attention if you experience:

  • Low blood sugar (especially when combined with other diabetes medications)
  • Dehydration
  • Burning sensation when passing urine
  • Cloudy urine
  • Pain during urination
  • Pain in the pelvis or mid-back
  • Swelling of the penis
  • Bullous pemphigoid
  • Pancreatitis
  • Fournier's gangrene
  • Allergic reactions
  • Diabetic ketoacidosis

Important Warnings

It's crucial to be aware of certain warnings before taking Glyxambi.

Who Should Not Take Glyxambi

Do not take Glyxambi if you are allergic to empagliflozin, linagliptin, or any of its ingredients.

Medical Conditions to Discuss

Inform your doctor if you have a history of type 1 diabetes, diabetic ketoacidosis, kidney problems, pancreatitis, or frequent urinary tract infections.

Pregnancy and Breastfeeding

Glyxambi should not be taken during pregnancy or while breastfeeding, as it may affect the developing baby.

Drug Interactions

Certain medications may interact with Glyxambi, affecting its efficacy.

  • Diuretics (water pills)
  • Rifampicin
  • Carbamazepine
  • Phenobarbital
  • Phenytoin
  • Lithium

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while on Glyxambi.

Alcohol

Drinking alcohol may increase the risk of low blood sugar levels.

Driving and Operating Machinery

Be careful when driving or using machinery until you know how Glyxambi affects you, as it can cause dizziness or lightheadedness.

Storage

Store Glyxambi tablets in a cool, dry place below 30°C, away from heat and moisture.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

Glyxambi starts to work by helping to lower blood sugar levels when taken as prescribed.

It does not matter if you take Glyxambi before or after food.

No, Glyxambi is not considered addictive.

Do not stop taking Glyxambi without consulting your doctor, as it may affect your blood sugar control.

Be cautious with alcohol, as it can increase the risk of low blood sugar.

Glyxambi is not known to cause weight gain; in fact, it may help with weight management.

Elderly patients should discuss their health conditions with their doctor before taking Glyxambi.

If you miss a dose, skip it if it's almost time for the next dose. Otherwise, take it as soon as you remember.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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