Gabitril (Tiagabine Hydrochloride Monohydrate)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Gabitril Used For?
Gabitril is an antiepileptic medication that helps control seizures in people with epilepsy when used alongside other seizure medications.
Primary Uses
Gabitril is used with other medicines to control some types of seizures (fits) in people with epilepsy. Epilepsy is a condition where you have repeated seizures, ranging from mild to severe.
How It Works
Gabitril works by increasing the level of a chemical in the brain called gamma-aminobutyric acid (GABA). This controls the signals in nerve cells so that seizures do not happen.
Good to know: This medicine helps control your condition but does not cure it, so you must take it every day even if you feel well.
How to Take Gabitril
Your doctor will determine the right dose for you and may start with a low dose, gradually increasing it to the lowest amount needed to control your epilepsy.
Dosage Instructions
Take Gabitril at the same times each day during or immediately after a meal. Swallow the tablets with a full glass of water. Your doctor may recommend starting with a low dose and slowly increasing to the lowest amount needed to control your epilepsy. Continue taking as long as your doctor tells you.
What If You Miss a Dose?
If it is almost time for your next dose, skip the missed dose and take your next dose when you are meant to. Otherwise, take it as soon as you remember and then go back to taking your medicine normally. Do not take a double dose to make up for the missed dose.
Important: Never double dose to make up for a missed dose. Do not stop taking suddenly or lower the dosage unless your doctor tells you to.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- tiredness
- dizziness
- nervousness (for no apparent reason)
- difficulty concentrating
- hostility
- difficulty speaking
- tremor
- diarrhea
Seek immediate medical attention if you experience:
- skin rash
- unusual bleeding or bruising
- feeling depressed
- problems with vision
- seeing, feeling or hearing things that are not there
- increase in number of seizures or different types of seizures
Important Warnings
There are important safety considerations and medical conditions to discuss with your doctor before taking Gabitril.
Who Should Not Take Gabitril
Do not use Gabitril if you are allergic to tiagabine or any ingredients, have severe liver disease, or are taking St John’s Wort (hypericum perforatum). Signs of allergic reaction include shortness of breath, wheezing, difficulty breathing, swelling of face/lips/tongue, or skin rash/hives.
Medical Conditions to Discuss
Tell your doctor if you have any other medical conditions, including anxiety disorders and depression, or if you take any medicines for other conditions.
Pregnancy and Breastfeeding
Check with your doctor if you are pregnant or intend to become pregnant. Talk to your doctor if you are breastfeeding or intend to breastfeed.
Mental Health Warning: Call your doctor immediately if you notice increasing signs of depression, unusual changes in mood or behavior, suicidal thoughts, suicidal behavior, or thoughts about self-harm.
Drug Interactions
Some medicines may interfere with Gabitril and affect how it works. Always tell your doctor about all medicines you are taking.
- Other epilepsy medicines such as phenytoin, carbamazepine, phenobarbitone and primidone
- St John’s Wort (hypericum perforatum)
Alcohol & Driving
Gabitril may affect your ability to drive or operate machinery and can interact with alcohol.
Alcohol
Tell your doctor if you drink alcohol. Alcohol may worsen dizziness or tiredness caused by Gabitril.
Driving and Operating Machinery
Be careful before you drive or use any machines or tools until you know how Gabitril affects you. Gabitril may cause dizziness and tiredness in some people.
Storage
Keep tablets in the pack until time to take them as they may not keep well if removed. Store in a cool dry place where temperature stays below 25°C. Keep away from moisture, heat, sunlight, and out of reach of children. Do not store in bathroom, near sink, in car, or on window sills.
Overdose Information
If you think you have taken too much Gabitril, seek urgent medical attention immediately. Phone the Poisons Information Centre (13 11 26), contact your doctor, or go to the nearest hospital Emergency Department even if there are no signs of discomfort. Overdose symptoms may include sleepiness, dizziness, tremor, unsteadiness, confusion, difficulty speaking, vomiting, breathing difficulties, headache, increased seizures, and coma.
Frequently Asked Questions
Take Gabitril during or immediately after a meal. If you take it on an empty stomach, it may cause stomach upset.
Do not stop taking Gabitril suddenly or lower the dosage unless your doctor tells you to. Stopping suddenly may make your condition worse. If you need to stop, your doctor may slowly reduce your dose first.
Tell your doctor if you drink alcohol. Alcohol may worsen the dizziness or tiredness that Gabitril can cause.
If it’s almost time for your next dose, skip the missed dose. Otherwise, take it as soon as you remember. Never take a double dose to make up for a missed dose.
There is not enough information to recommend Gabitril for children under 12 years of age.
Continue taking Gabitril for as long as your doctor tells you. This medicine helps control your condition but does not cure it, so you must take it every day even if you feel well.
Remind any doctor, dentist, or pharmacist you visit that you are using Gabitril, as it may interact with other treatments or medications.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.