Evenity (Romosozumab)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Evenity Used For?
Evenity is a medication that helps strengthen bones and reduce the risk of fractures in individuals with osteoporosis.
Primary Uses
Evenity is primarily used to treat osteoporosis in women after menopause and in men.
How It Works
Evenity works by inhibiting a protein called sclerostin, which helps build new bone and decreases the breakdown of existing bone.
Good to know: Evenity is not addictive.
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How to Take Evenity
Evenity is administered as an injection under the skin, typically by a healthcare professional or trained caregiver.
Dosage Instructions
The usual dose of Evenity is 210 mg, given as two injections of 105 mg each, once a month for 12 months.
What If You Miss a Dose?
If you miss a dose, take it as soon as possible and then schedule subsequent doses monthly from the last injection date. Do not double the dose.
Important: Never double the dose to make up for a missed one.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Injection site reactions (redness, bruising, pain)
- Cold-like symptoms (runny nose, sore throat, cough)
- Headache
- Joint pain
- Neck pain
- Swelling of hands, ankles, or feet
Seek immediate medical attention if you experience:
- Serious allergic reactions (rash, swelling of face, difficulty breathing)
- Symptoms of heart attack (chest pain, shortness of breath)
- Symptoms of stroke (headache, numbness, difficulty talking)
- Low calcium levels (muscle spasms, tingling)
- Jaw bone problems (loose teeth, mouth pain, non-healing sores)
Important Warnings
There are specific warnings and precautions to consider before using Evenity.
Who Should Not Take Evenity
Do not use Evenity if you have a history of heart attack or stroke, low calcium levels, or if you are allergic to any ingredients in Evenity.
Medical Conditions to Discuss
Discuss with your doctor if you have osteoporosis treatments, low calcium or vitamin D levels, dental issues, or cardiovascular problems.
Pregnancy and Breastfeeding
Evenity has not been tested in pregnant women and is not recommended during pregnancy. It is unknown if it passes into breast milk.
Drug Interactions
Certain medications may interact with Evenity and affect its effectiveness.
- Denosumab (Prolia)
- Bisphosphonates
Alcohol & Driving
There are no specific warnings regarding alcohol use with Evenity, but caution is advised.
Alcohol
No specific information on alcohol interactions with Evenity.
Driving and Operating Machinery
Evenity does not have known effects on the ability to drive, but be cautious after injections.
Storage
Store Evenity in the refrigerator between 2°C and 8°C. Do not freeze or expose to light. Once at room temperature, use within 30 days.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26.
Frequently Asked Questions
Evenity is administered monthly for 12 months, and its effects on bone strength may be observed over this period.
There are no specific dietary restrictions mentioned for Evenity.
No, Evenity is not considered addictive.
Consult your doctor about transitioning to another osteoporosis treatment after completing Evenity.
There are no known interactions between Evenity and alcohol, but caution is advised.
There is no information provided regarding weight gain associated with Evenity.
Consult your doctor to assess the safety of Evenity for elderly patients, especially those with pre-existing conditions.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.