Erivedge (Vismodegib)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Erivedge Used For?
Erivedge is a medication that contains vismodegib, which is used to treat adults with advanced basal cell carcinoma, a type of skin cancer.
Primary Uses
It is used for metastatic basal cell carcinoma or locally advanced basal cell carcinoma when surgery or radiation is not suitable.
How It Works
Erivedge works by inhibiting a key protein involved in the growth of cancer cells, potentially slowing or stopping their growth.
Good to know: This medication is not addictive.
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How to Take Erivedge
It is important to take Erivedge as prescribed by your doctor.
Dosage Instructions
The recommended dosage is one capsule (150mg) taken once daily, swallowed whole with a full glass of water, and can be taken with or without food.
What If You Miss a Dose?
If you miss a dose and it's almost time for your next dose, skip the missed dose and take the next one at the scheduled time. Do not double up on doses.
Important: Never take a double dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- nausea
- diarrhea
- constipation
- vomiting
- indigestion
- stomach pain
- fatigue
- unusual weakness
- weight loss
- decreased appetite
- changes in taste or loss of taste
- dehydration
- dry or sticky mouth
- low or no urine output
- dark urine
- no tears
- sunken eyes
- muscle spasms
- hair loss
- abnormal hair growth
- loss of menstrual periods
- chest, back, side, or limb pain
Seek immediate medical attention if you experience:
- shortness of breath
- difficulty breathing
- chest tightness
- wheezing
- swelling of the face, lips, tongue, or other body parts
- rash, itching, or hives
Important Warnings
There are several important warnings to consider before taking Erivedge.
Who Should Not Take Erivedge
Do not take Erivedge if you are pregnant, planning to become pregnant, or breastfeeding. Women must use two forms of contraception during treatment and for 24 months after the last dose.
Medical Conditions to Discuss
Discuss any kidney problems or allergies to vismodegib or its ingredients with your doctor.
Pregnancy and Breastfeeding
Erivedge can cause severe birth defects and should not be taken during pregnancy or breastfeeding. It may affect a developing baby.
Drug Interactions
Some medications may interact with Erivedge and affect its effectiveness.
- ezetimibe
- statins (e.g., atorvastatin, fluvastatin, pravastatin, rosuvastatin, simvastatin)
- bosentan
- glibenclamide
- valsartan
- olmesartan
Alcohol & Driving
Be cautious when consuming alcohol and operating vehicles or machinery while taking Erivedge.
Alcohol
Limit alcohol consumption while on this medication.
Driving and Operating Machinery
Use caution when driving or operating machinery until you know how Erivedge affects you.
Storage
Store Erivedge capsules in a cool, dry place below 30°C, in the original bottle with the cap tightly closed. Avoid storing in bathrooms or near sinks.
Overdose Information
If you suspect an overdose of Erivedge, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
The time it takes for Erivedge to work can vary by individual; consult your doctor for specific expectations.
Yes, Erivedge can be taken with or without food.
No, Erivedge is not considered addictive.
Do not stop taking Erivedge without consulting your doctor, as this may affect your treatment.
It is advisable to limit alcohol consumption while taking Erivedge.
Weight changes can occur; consult your doctor if you have concerns.
Elderly patients should discuss their specific health conditions with their doctor before taking Erivedge.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.