Enspryng (Satralizumab)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name

satralizumab

Drug Class

monoclonal antibody

Used For

treatment of neuromyelitis optica spectrum disorders (NMOSD)

How Taken

injection under the skin every four weeks

What Is Enspryng Used For?

Enspryng is a medication used to manage neuromyelitis optica spectrum disorders (NMOSD) in adults who have tested positive for the AQP4-IgG antibody.

Primary Uses

Enspryng is primarily used to treat NMOSD, an autoimmune disease affecting the central nervous system.

How It Works

Enspryng functions by blocking interleukin-6 (IL-6), a protein that plays a role in inflammation, which is elevated in NMOSD.

Good to know: Enspryng is not considered addictive.

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How to Take Enspryng

Enspryng is administered via subcutaneous injection using a pre-filled syringe.

Dosage Instructions

Each injection contains 120 mg of satralizumab. The first three injections are given every two weeks, followed by maintenance doses every four weeks.

What If You Miss a Dose?

If you miss a scheduled injection, consult your doctor for guidance. Do not take a double dose.

Important: Never double dose to make up for a missed injection.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

headache
injection site reactions (hot flushes, skin reddening, itching, rash, pain)
joint pain
low fibrinogen levels

Seek immediate medical attention if you experience:

allergic reactions (shortness of breath, swelling of face, rash, hives)
serious infections

Important Warnings

It is crucial to be aware of potential risks and contraindications before using Enspryng.

Who Should Not Take Enspryng

Do not use Enspryng if you have a known allergy to satralizumab or any of its ingredients.

Medical Conditions to Discuss

Discuss any existing medical conditions, other medications you are taking, or if you are pregnant or breastfeeding.

Pregnancy and Breastfeeding

Women who can become pregnant must use effective contraception during treatment and for three months after the last injection. Consult your doctor if you are pregnant or breastfeeding.

Elderly Patients With Dementia: The safety of Enspryng in elderly patients over 74 years has not been established.

Drug Interactions

Certain medications may interact with Enspryng, affecting its efficacy.

warfarin
carbamazepine
phenytoin
theophylline

Alcohol & Driving

Be cautious when driving or operating machinery until you know how Enspryng affects you.

Alcohol

Consult your doctor regarding alcohol consumption while on Enspryng.

Driving and Operating Machinery

Ensure you are aware of how this medication affects your ability to drive or operate machinery.

Storage

Store Enspryng in the refrigerator between 2°C and 8°C. Do not freeze or shake. If kept at room temperature, do not exceed 8 days at temperatures below 30°C.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.

Frequently Asked Questions

The exact time for Enspryng to take effect can vary, but it is typically administered every four weeks after initial doses.

There are no specific dietary restrictions mentioned for taking Enspryng.

No, Enspryng is not considered addictive.

Do not stop using Enspryng without consulting your doctor, as this may lead to a relapse of symptoms.