Empliciti (Elotuzumab)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
elotuzumab
Drug Class
monoclonal antibody
Used For
treatment of multiple myeloma in adults
How Taken
administered by intravenous infusion under medical supervision

What Is Empliciti Used For?

Empliciti is a medication that contains the active ingredient elotuzumab, used to treat multiple myeloma, a type of cancer affecting the bone marrow.

Primary Uses

Empliciti is primarily used to treat multiple myeloma in adults, typically in combination with other medications.

How It Works

Elotuzumab targets a protein called SLAMF7 found on multiple myeloma cells and certain immune cells, stimulating the immune system to attack and destroy cancer cells.

Good to know: Empliciti is not considered addictive.

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How to Take Empliciti

Empliciti is administered through an intravenous infusion, ensuring that it is given safely under the supervision of a healthcare professional.

Dosage Instructions

The recommended dose of Empliciti is 10 mg per kilogram of body weight, given every week for the first two cycles and every two weeks thereafter, in combination with lenalidomide and dexamethasone.

What If You Miss a Dose?

If a dose is missed, your doctor will determine how to continue your treatment based on the overall regimen.

Important: Never double dose if you miss a treatment; consult your doctor for guidance.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • weight decrease
  • low white blood cell count
  • cough
  • chest pain
  • night sweats
  • mood changes
  • decreased sensitivity in the skin
  • painful skin rash (shingles, herpes zoster)
  • allergic reactions (hypersensitivity)

Seek immediate medical attention if you experience:

  • infusion reactions (fever, chills, high blood pressure)
  • signs of infection (fever, shortness of breath, flu-like symptoms, painful rash)

Important Warnings

Before starting Empliciti, it is crucial to understand potential risks and contraindications.

Who Should Not Take Empliciti

Do not use Empliciti if you have a known allergy to elotuzumab or any of its ingredients.

Medical Conditions to Discuss

Discuss any existing medical conditions, especially liver issues, infections, or if you are at risk for new cancers.

Pregnancy and Breastfeeding

Empliciti should not be used during pregnancy unless specifically recommended by a doctor. Effective contraception is advised during treatment. The effects on breastfeeding are unknown, so consult your doctor if you are breastfeeding.

Elderly Patients With Dementia: Elderly patients, particularly those with dementia, should use caution when taking Empliciti.

Drug Interactions

Certain medications may interact with Empliciti, affecting its efficacy.

Grapefruit interaction: Consult your doctor about any potential grapefruit interactions.

  • lenalidomide
  • dexamethasone

Alcohol & Driving

Empliciti is unlikely to impair your ability to drive or operate machinery, but caution is advised.

Alcohol

Consult your doctor regarding alcohol consumption while on Empliciti.

Driving and Operating Machinery

If you experience infusion reactions, avoid driving or operating machinery until symptoms resolve.

Storage

Store Empliciti as directed by your healthcare provider, typically in a cool, dry place away from light.

Overdose Information

Overdosing on Empliciti is unlikely as it is administered by a healthcare professional. In case of an overdose, medical staff will monitor for side effects.

Frequently Asked Questions

The time it takes for Empliciti to show effects can vary by individual and treatment plan.

Empliciti is administered via infusion, so food intake does not affect its administration.

No, Empliciti is not considered addictive.

Do not stop taking Empliciti without consulting your doctor, as this may affect treatment outcomes.

Consult your doctor regarding alcohol consumption while on Empliciti.

Weight decrease is a common side effect, not weight gain.

Elderly patients should use caution and consult their doctor before starting Empliciti.

If a dose is missed, your doctor will guide you on how to continue your treatment.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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