Eloctate (Efmoroctocog Alfa)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Eloctate Used For?
Eloctate contains efmoroctocog alfa, a factor VIII protein that helps your blood form clots properly. It's specifically designed for people with haemophilia A who don't have enough natural factor VIII to control bleeding.
Primary Uses
Eloctate is used to control and prevent bleeding episodes, routinely prevent and reduce the frequency of bleeding episodes, and reduce bleeding before, during, and after surgery in people with haemophilia A.
How It Works
People with haemophilia A lack sufficient factor VIII to control bleeding. Eloctate works by replacing factor VIII to enable blood to clot normally.
Not for Von Willebrand's Disease: Eloctate does not contain von Willebrand factor, so it is not suitable for use in Von Willebrand's disease.
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How to Take Eloctate
Eloctate is given as a slow injection directly into your vein. It comes as a powder in a vial that must be mixed with the provided solvent before use. Your doctor will determine the right dose for you.
Dosage Instructions
Your doctor will decide what dose you will receive based on your individual need for replacement factor VIII therapy. The dose may change during your treatment. Mix the powder with the provided solvent only when ready to use. Do not shake when mixing as this can damage the medicine. After mixing, the solution should be clear to slightly rainbow-like and colorless. Do not inject if discolored, cloudy, or contains particles. If mixed but interrupted, you can keep the solution for up to 6 hours at below 30°C, protected from direct sunlight.
What If You Miss a Dose?
If you miss your dose at the usual time, use your dose as soon as you remember and resume your normal dosing schedule. Do not use a double dose to make up for the missed dose.
Important: Do not stop using Eloctate or change the dosage without checking with your doctor. Eloctate is for single use in one patient only.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Joint pain or swelling
- Muscle aches, tenderness or weakness
- General feeling of discomfort
- Feeling hot or cold
- Headache
- Stomach pain
- High or low blood pressure
- Dizziness
- Cough
- Light headedness
- Back pain
- Slow heartbeat
- Chest pain
- Rash
- Loss of taste
Seek immediate medical attention if you experience:
- Factor VIII inhibition (easily bruising or bleeding due to factor VIII inhibition)
- Allergic reactions with shortness of breath, wheezing or difficulty breathing
- Chest pain or discomfort
- Swelling of the face, lips, tongue or other parts of the body
- Rash or hives
Important Warnings
Before using Eloctate, make sure your doctor knows about all your medical conditions and medications. There are important safety considerations to discuss.
Who Should Not Take Eloctate
Do not use Eloctate if you have ever had an allergic reaction to Eloctate, efmoroctocog alfa, other factor VIII replacement factors, or any of the ingredients listed in the medication guide.
Medical Conditions to Discuss
Tell your doctor if you have any other medical conditions or take any other medicines. Your body can make antibodies called 'inhibitors' against Eloctate which may stop it from working properly. Eloctate may increase the risk of abnormal blood clots forming if you are at risk of developing blood clots.
Pregnancy and Breastfeeding
Check with your doctor if you are pregnant or intend to become pregnant. There is no information on the use of Eloctate during pregnancy. Talk to your doctor if you are breastfeeding or plan to breastfeed, as it is not known whether Eloctate passes into breast milk. Your doctor will discuss the risks and benefits in both situations.
Tell your doctor immediately: Contact your doctor right away if bleeding is not controlled after using Eloctate or if you become pregnant while on treatment.
Drug Interactions
Tell your doctor, Haemophilia Treatment Centre, or pharmacist about all medicines you are taking, including vitamins and supplements bought without a prescription.
Alcohol & Driving
Be careful when driving or using machinery until you know how Eloctate affects you.
Driving and Operating Machinery
Be careful before you drive or use any machines or tools until you know how Eloctate affects you.
Storage
Store Eloctate in the refrigerator at 2°C to 8°C. Do not freeze. Keep in the pack until ready to use, protected from light. If necessary, you can keep Eloctate out of the refrigerator for a single 6-month period at below 30°C in a cool, dry place. Record the date it was removed from refrigeration. Once mixed, keep at room temperature (below 30°C) for up to 6 hours, protected from direct sunlight. Do not use after the expiry date or if packaging is damaged.
Overdose Information
If you think you or anyone else may have used too much Eloctate, seek urgent medical attention immediately. Contact your doctor, go to the Emergency Department at your nearest hospital, or phone the Poisons Information Centre (13 11 26 in Australia or 0800 764 766 in New Zealand), even if there are no signs of discomfort.
Frequently Asked Questions
Eloctate works by replacing factor VIII to help your blood clot. Your doctor will monitor your response and may adjust your dose as needed during treatment.
Tell your doctor immediately if bleeding is not controlled after using Eloctate. This is important information your healthcare team needs to know right away.
Mix the Eloctate powder with the provided solvent only when ready to use. Do not shake when mixing as this can damage the medicine. The mixed solution should be clear to slightly rainbow-like and colorless.
If you miss your dose, use it as soon as you remember and resume your normal dosing schedule. Do not use a double dose to make up for the missed dose.
Do not stop using Eloctate or change the dosage without checking with your doctor first, unless you have an allergic reaction.
Once mixed, you can keep Eloctate at room temperature (below 30°C) for up to 6 hours, protected from direct sunlight. Do not freeze the mixed solution.
Remind any doctor, dentist, or pharmacist you visit that you are using Eloctate. If you are about to have blood tests, tell your doctor that you are using this medication.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.