Ebglyss (Lebrikizumab)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
lebrikizumab
Drug Class
monoclonal antibodies
Used For
treatment of moderate to severe atopic dermatitis in adults and adolescents (12 years and older)
How Taken
subcutaneous injection every 2 weeks or every 4 weeks

What Is Ebglyss Used For?

Ebglyss is a medication that contains lebrikizumab, which is used to manage moderate to severe atopic dermatitis, also known as atopic eczema, in adults and adolescents aged 12 years and older.

Primary Uses

Ebglyss is primarily used for treating moderate to severe atopic dermatitis.

How It Works

Ebglyss works by blocking interleukin-13 (IL-13), a protein that contributes to inflammation in atopic dermatitis.

Good to know: Ebglyss is not considered addictive.

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How to Take Ebglyss

Ebglyss is administered via subcutaneous injection, and it's important to follow your doctor's instructions carefully.

Dosage Instructions

The initial dose is two 250 mg autoinjectors injected under the skin at Week 0 and Week 2. After that, the maintenance dose is one 250 mg autoinjector every 4 weeks starting from Week 16, unless otherwise directed by your doctor.

What If You Miss a Dose?

If you miss a dose, inject it as soon as you remember. Then, continue with your next scheduled dose.

Important: Never double the dose if you miss one.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • injection site reactions
  • eye infection
  • dry eyes
  • eye pain
  • blurry vision
  • sensitivity to light
  • eye and eyelid inflammation

Seek immediate medical attention if you experience:

  • hypersensitivity reactions
  • breathing problems
  • swelling of the face or throat
  • hives
  • dizziness
  • skin rash
  • cramps in the stomach
  • shingles symptoms

Important Warnings

There are several important warnings to consider before using Ebglyss.

Who Should Not Take Ebglyss

Do not use Ebglyss if you are allergic to lebrikizumab or any of its ingredients, if the solution is cloudy or discolored, or if it has expired.

Medical Conditions to Discuss

Discuss any existing medical conditions with your doctor, especially if you have a parasitic infection or eye problems.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as the effects of Ebglyss during pregnancy are not known.

Drug Interactions

Certain medications may interact with Ebglyss, affecting its efficacy.

Alcohol & Driving

Ebglyss is unlikely to affect your ability to drive or operate machinery.

Alcohol

There are no specific warnings regarding alcohol consumption while taking Ebglyss.

Driving and Operating Machinery

Ebglyss should not impair your ability to drive or use machinery.

Storage

Store Ebglyss in the refrigerator at 2°C to 8°C, protected from light. It can be kept at room temperature (up to 30°C) for a maximum of 7 days after removal from the refrigerator.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26.

Frequently Asked Questions

The onset of action may vary, and your doctor will monitor your response to the treatment.

There are no specific dietary restrictions mentioned for Ebglyss.

Ebglyss is not considered addictive.

Do not stop taking Ebglyss without consulting your doctor, as this may affect your condition.

There are no specific warnings regarding alcohol consumption while on Ebglyss.

Weight gain is not mentioned as a side effect of Ebglyss.

Consult your doctor for advice on the safety of Ebglyss in elderly patients.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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