Dynastat (Parecoxib Sodium)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Dynastat Used For?
Dynastat is a prescription pain medication specifically designed for post-surgical care. It belongs to a special group of anti-inflammatory drugs called Coxibs.
Primary Uses
Dynastat is used to relieve pain and reduce swelling and soreness that may occur after surgery.
How It Works
Dynastat is a type of non-steroidal anti-inflammatory drug (NSAID) that belongs to a group of medicines called Coxibs, which work to reduce pain and inflammation.
How to Take Dynastat
Dynastat is only given in a hospital setting by trained medical professionals. You will not need to administer this medication yourself.
Dosage Instructions
Dynastat will be given to you by a doctor or nurse in the hospital. Your doctor will decide how much Dynastat you need based on factors like liver or kidney problems, your age, weight, or other medicines you may be taking.
What If You Miss a Dose?
Since Dynastat is given by healthcare professionals in a hospital setting, missing doses is not a concern for patients.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Vomiting
- Heartburn
- Constipation
- Diarrhea
- Stomach pain, wind, bloating
- Dry mouth, feeling thirsty
- Back pain
- Earache
- Pain after tooth extraction
- Sore throat
- Low or high blood pressure
- Dizziness or light-headedness
- Trouble sleeping
- Irritability, agitation
- Feeling numb
- Increased sweating
- Passing less urine than normal
- Loss of appetite
Seek immediate medical attention if you experience:
- Allergic reactions (wheezing, swelling of face, lips, mouth, tongue, or throat)
- Skin rash, hives, blistering or peeling of skin
- Bleeding or bruising more easily than normal
- Complications with skin healing after operations
- Yellowing of skin or eyes (jaundice)
- Slow or irregular heartbeat
- Unusual weight gain or loss
- Severe stomach or throat pain
- Vomiting blood or bloody/black bowel motions
- Blistering and bleeding in lips, eyes, mouth, nose, and genitals
- Swelling under armpit or neck
- Joint pain, muscle weakness
- Tiredness, shortness of breath, looking pale
- Discharge from wounds
- Feeling faint, chest pain
- Severe headache, fever, stiff neck, sensitivity to light
Important Warnings
There are several important conditions and situations where Dynastat should not be used, and others where special caution is needed.
Who Should Not Take Dynastat
You must not receive Dynastat if you: have ever had an allergic reaction to parecoxib or any ingredients; take other pain medicines, anti-inflammatory drugs, or sulfonamide antibiotics; are about to have heart or blood vessel surgery; have had heart disease, blood vessel disease, or stroke; have severe liver problems; are in the third trimester of pregnancy; or are breastfeeding.
Medical Conditions to Discuss
Tell your doctor if you have or have had: kidney or liver problems; heart diseases or blood vessel diseases; stroke; diabetes; high cholesterol; high or low blood pressure; blood clots; water retention; dehydration; asthma; skin problems after taking similar medicines; stomach ulcers or bloody/black stools; if you smoke; or have a fever or infection.
Pregnancy and Breastfeeding
You should not receive Dynastat if you are in the third trimester of pregnancy or if you are breastfeeding. Use during the first two trimesters is not recommended as it may affect your developing baby and labor. Dynastat passes into breast milk, so you need to stop breastfeeding during treatment. Related medicines have been associated with reversible infertility in some women and increased risk of spontaneous abortion.
Infection Warning: If you are given Dynastat when you have an infection, it may hide a fever (a sign of an infection).
Drug Interactions
Several types of medications can interfere with Dynastat and affect how it works. Always tell your doctor about all medicines you’re taking.
- High blood pressure medicines (losartan, olmersartan)
- Heart disease medicines (captopril, enalapril, monopril, lisinopril, accupril, ramipril)
- Water tablets/diuretics (hydrochlorothiazide, indapamide)
- Pain and inflammation medicines (aspirin, other NSAIDs)
- Corticosteroids for allergies and inflammation (prednisolone)
- Blood clot prevention medicines (warfarin, apixaban, rivaroxaban, dabigatran)
- Mental health medicines (lithium salts, fluoxetine, sertraline)
- Diabetes medicines (glibenclamide)
- Arthritis and cancer medicines (methotrexate)
- Organ transplant medicines (ciclosporin, tacrolimus)
- Antifungal medicines (fluconazole, ketoconazole)
Alcohol & Driving
Dynastat can affect your ability to drive and may interact with alcohol, so it’s important to take precautions.
Alcohol
Tell your doctor or nurse if you drink alcohol, as this information is important for your treatment.
Driving and Operating Machinery
This medicine may cause dizziness or light-headedness in some people. If you experience these symptoms, do not drive, operate machinery, or do anything else that could be dangerous. Be careful before you drive or use any machines or tools until you know how Dynastat affects you.
Storage
Dynastat is stored in the hospital, and the hospital is responsible for storing and disposing of any unused product correctly. You do not need to worry about storage as a patient.
Overdose Information
Since Dynastat is given in a hospital under medical supervision, overdose is very unlikely. However, if you experience any concerning symptoms, tell your doctor or nurse immediately. Signs of too much Dynastat may include feeling tired, drowsy, sick, having stomach pains, or other abdominal problems. If you’re concerned about an overdose, immediately tell your doctor or nurse, phone the Poisons Information Centre (13 11 26), or go to the Emergency Department at your nearest hospital, even if there are no signs of discomfort.
Frequently Asked Questions
The source doesn’t specify how quickly Dynastat works, but as an injection given for post-surgical pain, it’s designed to provide pain relief after surgery. Your doctor will monitor your response to the medication.
You must not take other medicines to relieve pain, reduce swelling, or sulfonamide antibiotics while receiving Dynastat. Always tell your doctor about any other medications you’re taking, and don’t take any other medicines unless your doctor is aware of it.
The source material doesn’t mention addiction potential for Dynastat. However, it’s a prescription medication that should only be used as directed by your healthcare provider.
You should tell your doctor or nurse if you drink alcohol, as this information is important for your treatment with Dynastat.
If you develop signs of allergic reaction such as wheezing, swelling of the face, lips, mouth, tongue or throat, difficulty swallowing or breathing, or extensive skin rashes, call your doctor straight away or go to the Emergency Department at your nearest hospital immediately.
No, you should not receive Dynastat if you are in the third trimester of pregnancy or if you are breastfeeding. Use during the first two trimesters is not recommended as it may affect your developing baby. Dynastat passes into breast milk, so breastfeeding must be stopped during treatment.
You should not receive Dynastat if you have allergies to parecoxib or similar medications, are taking certain other pain medications, are having heart or blood vessel surgery, have heart disease or stroke history, have severe liver problems, are in late pregnancy, or are breastfeeding.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.