Duodart (Dutasteride And Tamsulosin Hydrochloride)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
dutasteride and tamsulosin hydrochloride
Drug Class
5-alpha reductase enzyme inhibitors and alpha-blockers
Used For
Treatment of benign prostatic hyperplasia (BPH) in men
How Taken
One capsule taken once daily, approximately 30 minutes after the same meal

What Is Duodart Used For?

Duodart is a medication prescribed to men suffering from benign prostatic hyperplasia (BPH), a condition characterized by the non-cancerous enlargement of the prostate gland.

Primary Uses

Duodart is primarily used to alleviate symptoms associated with BPH, such as difficulty starting urination, a weak urinary stream, and frequent urination, especially at night.

How It Works

The dutasteride component reduces the production of dihydrotestosterone (DHT), leading to a decrease in prostate size. Tamsulosin hydrochloride relaxes the smooth muscles in the prostate, making it easier to urinate.

Good to know: Duodart is not addictive.

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How to Take Duodart

It is important to take Duodart as prescribed by your doctor.

Dosage Instructions

The usual dosage is one capsule daily, taken approximately 30 minutes after the same meal each day. Do not take on an empty stomach.

What If You Miss a Dose?

If you forget to take a dose, skip it and take your next dose at the regular time. Do not double the dose to make up for a missed one.

Important: Never take a double dose to compensate for a missed dose.

Available Tablet Strengths

0.5mg
0.5mg Tablet Brown, Oblong • GS 7CZ

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Impotence
  • Decreased libido
  • Difficulty with ejaculation
  • Breast swelling or tenderness
  • Dizziness
  • Constipation
  • Diarrhea
  • Vomiting
  • Fast heartbeat
  • Weakness or loss of strength
  • Low blood pressure upon standing
  • Itchy, blocked, or runny nose

Seek immediate medical attention if you experience:

  • Allergic reactions (wheezing, difficulty breathing, swelling of lips or mouth, rash)
  • Serious skin reactions (widespread rash, blisters, peeling skin)
  • Breast lumps or nipple discharge
  • Testicular pain or swelling
  • Prolonged erection unrelated to sexual activity
  • Low blood pressure upon standing

Important Warnings

There are several important warnings to consider before taking Duodart.

Who Should Not Take Duodart

Do not use Duodart if you are allergic to dutasteride, tamsulosin hydrochloride, or any of its ingredients. It is also not suitable for women or children, and those with a history of orthostatic hypotension.

Medical Conditions to Discuss

Consult your doctor if you have liver or kidney conditions, are planning cataract surgery, or are taking medications to lower blood pressure.

Pregnancy and Breastfeeding

Women who are pregnant or may become pregnant should avoid handling Duodart capsules, as exposure could affect male fetal development. Discuss with your doctor if your partner is pregnant or breastfeeding.

Drug Interactions

Certain medications may interact with Duodart, affecting its efficacy.

  • Potent inhibitors of CYP3A4 (e.g., ritonavir, indinavir, nefazodone, itraconazole, ketoconazole)
  • Antifungal medications like ketoconazole
  • Selective serotonin reuptake inhibitors (e.g., paroxetine)

Alcohol & Driving

Be cautious when consuming alcohol or driving while taking Duodart.

Alcohol

Alcohol may increase the risk of dizziness or light-headedness.

Driving and Operating Machinery

Do not drive or operate machinery until you know how Duodart affects you, as it can cause dizziness and light-headedness.

Storage

Store Duodart capsules in their original bottle below 25°C, away from moisture and heat. Keep out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 13 11 26 in Australia.

Frequently Asked Questions

It may take several months to notice an improvement in symptoms.

Yes, it should be taken approximately 30 minutes after the same meal each day.

No, Duodart is not addictive.

Do not stop taking Duodart suddenly without consulting your doctor, as it may affect your symptoms.

Be cautious with alcohol, as it may increase the risk of dizziness.

Weight gain is not listed as a common side effect of Duodart.

Elderly patients should discuss their overall health with their doctor before taking Duodart.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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