Desfax (Desvenlafaxine)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
desvenlafaxine
Drug Class
Serotonin-Noradrenaline Reuptake Inhibitors (SNRIs)
Used For
Treatment and prevention of relapse of depression
How Taken
Oral tablet, usually taken once daily

What Is Desfax Used For?

Desfax is a medication that helps manage depression by increasing the levels of serotonin and noradrenaline in the brain.

Primary Uses

Desfax is primarily used for treating depression and preventing its relapse.

How It Works

Desfax works by enhancing the activity of serotonin and noradrenaline, which are neurotransmitters that help regulate mood.

Good to know: Desfax is not considered addictive.

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How to Take Desfax

Follow your doctor's instructions on how to take Desfax for the best results.

Dosage Instructions

The usual dose is 50 mg taken once daily, with or without food. Swallow the tablet whole with a glass of water.

What If You Miss a Dose?

If you miss a dose and it's less than 12 hours until your next dose, skip the missed dose. Otherwise, take it as soon as you remember, but do not double the dose.

Important: Never take a double dose to make up for a missed one.

Available Tablet Strengths

50mg
50mg Tablet Light pink, Diamond • L189
100mg
100mg Tablet Dark brown to red, Diamond • L190

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Nausea
  • Diarrhea
  • Constipation
  • Difficulty passing urine
  • Anxiety
  • Irritability
  • Dizziness
  • Fatigue
  • Excessive sweating
  • Weight changes

Seek immediate medical attention if you experience:

  • Neuroleptic malignant syndrome symptoms (high fever, muscle stiffness, altered mental state)
  • Serotonin syndrome symptoms (high fever, shivering, muscle stiffness, seizures)
  • Thoughts of suicide or self-harm

Impulse Control Issues

Some patients may experience impulse control issues, including compulsive behaviors.

Important Warnings

There are several important considerations to keep in mind when taking Desfax.

Who Should Not Take Desfax

Do not use Desfax if you are allergic to desvenlafaxine, venlafaxine, or any ingredients in the medication. Avoid it if you have taken monoamine oxidase inhibitors in the last 14 days.

Medical Conditions to Discuss

Discuss with your doctor if you have a history of seizures, bipolar disorder, blood pressure issues, glaucoma, or any liver or kidney problems.

Pregnancy and Breastfeeding

Desfax is not recommended during pregnancy or breastfeeding due to potential risks to the baby.

Elderly Patients With Dementia: Elderly patients, especially those with dementia, should use Desfax with caution.

Drug Interactions

Certain medications can interact with Desfax and affect its effectiveness.

Grapefruit interaction: Avoid grapefruit while taking Desfax, as it may affect how the medication works.

  • Monoamine oxidase inhibitors
  • Other medications for bipolar disorder, depression, anxiety, or obsessive-compulsive disorder
  • Drugs affecting serotonin levels (e.g., tramadol, fentanyl)
  • Medications for ADHD
  • Weight loss medications
  • Triptans
  • Blood thinners (e.g., aspirin, NSAIDs, warfarin)

Alcohol & Driving

Be cautious with alcohol consumption and operating machinery while on Desfax.

Alcohol

Avoid drinking alcohol while taking Desfax, as it may increase side effects.

Driving and Operating Machinery

Be careful when driving or using machinery until you know how Desfax affects you, as it may cause drowsiness.

Temperature Regulation

Monitor your body temperature, as Desfax may affect how your body regulates temperature.

Storage

Store Desfax in its original packaging in a cool, dry place below 25°C, away from moisture and heat.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Contact your doctor or the Poisons Information Centre at 1311 26.

Frequently Asked Questions

You may start to feel better after about two weeks, but it can take several weeks to feel the full effect.

Yes, you can take Desfax with or without food.

Desfax is not considered addictive.

Do not stop taking Desfax suddenly without consulting your doctor, as it may lead to withdrawal symptoms.

It is advised to avoid alcohol while taking Desfax due to potential increased side effects.

Weight changes, including gain or loss, can occur while taking Desfax.

Elderly patients should use Desfax with caution, especially those with dementia.

If you miss a dose, skip it if it's less than 12 hours until your next dose. Otherwise, take it as soon as you remember.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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