Deptran (Doxepin (As Hydrochloride))

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
doxepin (as hydrochloride)
Drug Class
tricyclic antidepressants (TCAs)
Used For
treatment of depression
How Taken
oral capsules or tablets, taken daily

What Is Deptran Used For?

Deptran is a medication that contains doxepin, which is used primarily to treat depression. It belongs to a class of drugs known as tricyclic antidepressants.

Primary Uses

Deptran is mainly used for the treatment of depression.

How It Works

Deptran works by affecting brain chemicals called amines that help regulate mood.

Good to know: Deptran is not considered addictive.

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How to Take Deptran

It is important to follow your doctor's instructions when taking Deptran to ensure its effectiveness.

Dosage Instructions

The typical dosage of Deptran ranges from 30 mg to 300 mg daily, as determined by your doctor.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up on doses.

Important: Never take a double dose to compensate for a missed dose.

Available Tablet Strengths

10mg
10mg Tablet White, Capsule • DP 10
25mg
25mg Tablet Blue, Capsule • N/A
50mg
50mg Tablet Light violet, Tablet • DN over 50

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • drowsiness
  • dizziness
  • light-headedness
  • difficulty sleeping
  • dry mouth
  • blurred vision
  • constipation
  • diarrhea
  • nausea

Seek immediate medical attention if you experience:

  • anxiety
  • aggressive behavior
  • fast or irregular heartbeat
  • chest pain
  • unusual bruising or bleeding
  • thoughts of suicide or self-harm

Impulse Control Issues

Monitor for any changes in behavior, including increased impulsivity or self-harm.

Important Warnings

There are several important warnings to consider before taking Deptran.

Who Should Not Take Deptran

Do not take Deptran if you are allergic to doxepin or other tricyclic antidepressants, have glaucoma, or are taking monoamine oxidase inhibitors (MAOIs).

Medical Conditions to Discuss

Discuss any history of mental illness, heart disease, liver or kidney issues, and diabetes with your doctor.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant or breastfeeding, as Deptran can pass into breast milk.

Elderly Patients With Dementia: Use caution when prescribing Deptran to elderly patients, especially those with dementia.

Drug Interactions

Certain medications may interact with Deptran, affecting its effectiveness.

Grapefruit interaction: Grapefruit may affect how Deptran works.

  • Monoamine oxidase inhibitors (MAOIs)
  • Other antidepressants (e.g., fluoxetine, sertraline, paroxetine)
  • Cimetidine
  • Diabetes medications (e.g., glibenclamide, glipizide)
  • Anti-anxiety medications (e.g., diazepam, oxazepam)
  • Tranquilizers (e.g., risperidone, chlorpromazine)
  • Medications for heart rhythm control (e.g., isosorbide mononitrate, flecainide)
  • Epilepsy medications (e.g., phenytoin, carbamazepine)
  • Stimulants (e.g., dexamphetamine)
  • Buprenorphine

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles while taking Deptran.

Alcohol

Combining alcohol with Deptran may increase drowsiness and dizziness.

Driving and Operating Machinery

Deptran may impair your ability to drive or operate machinery.

Temperature Regulation

Be aware that Deptran may affect your body's ability to regulate temperature.

Storage

Store Deptran capsules below 25°C and tablets below 30°C in a cool, dry place away from moisture and sunlight.

Overdose Information

In case of overdose, seek immediate medical attention. Symptoms may include drowsiness, confusion, and abnormal heartbeat.

Frequently Asked Questions

It may take 2 to 3 weeks to feel the full benefits of Deptran.

Deptran can be taken with or without food.

No, Deptran is not considered addictive.

Do not stop taking Deptran suddenly; consult your doctor for a gradual reduction.

Be cautious with alcohol, as it can increase drowsiness and dizziness.

Weight changes are possible; consult your doctor if concerned.

Elderly patients should use caution and consult their doctor.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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