Combigan (Brimonidine Tartrate And Timolol Maleate)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
Brimonidine tartrate and Timolol maleate
Drug Class
Alpha-adrenergic agonists
Used For
Lowering eye pressure and treating glaucoma
How Taken
Eye drops, usually one drop in the eye(s) two times a day

What Is Combigan Used For?

Combigan is an eye drop medication that helps reduce elevated pressure in the eyes, commonly used for managing glaucoma.

Primary Uses

It is primarily used to treat glaucoma, a condition characterized by increased fluid pressure in the eye which can lead to vision loss.

How It Works

Combigan works by decreasing the production of fluid in the eye and improving its drainage, thereby lowering eye pressure.

Good to know: Combigan is not addictive.

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How to Take Combigan

Follow your doctor's instructions on how to use Combigan eye drops for optimal results.

Dosage Instructions

The typical dosage is one drop in the affected eye(s) twice daily, approximately 12 hours apart.

What If You Miss a Dose?

If you forget a dose, use it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue your regular schedule. Do not double the dose.

Important: Never double dose to make up for a missed dose.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Redness of the eye
  • Burning or stinging sensation
  • Blurred vision
  • Tearing

Seek immediate medical attention if you experience:

  • Severe allergic reactions
  • Difficulty breathing
  • Heart failure
  • Fast or irregular heartbeat
  • High blood pressure

Impulse Control Issues

No specific information about impulse control issues was mentioned.

Important Warnings

Be aware of specific conditions and allergies that may prevent you from using Combigan.

Who Should Not Take Combigan

Do not use Combigan if you are allergic to its ingredients, have certain heart conditions, or are under 2 years of age.

Medical Conditions to Discuss

Inform your doctor if you have liver or kidney disease, asthma, depression, diabetes, or any history of heart issues.

Pregnancy and Breastfeeding

Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, as they will evaluate the risks and benefits.

Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.

Drug Interactions

Combigan may interact with other medications, affecting how they work.

Grapefruit interaction: No specific grapefruit interaction mentioned.

  • Medicines for high blood pressure
  • Monoamine oxidase inhibitors
  • Tricyclic antidepressants
  • Sedatives and antihistamines
  • Sympathomimetic medications
  • Antidiabetic agents
  • Certain heart medications

Alcohol & Driving

Combigan may cause drowsiness, which can be worsened by alcohol consumption.

Alcohol

Avoid alcohol as it can enhance drowsiness caused by Combigan.

Driving and Operating Machinery

Wait until your vision is clear after using Combigan before driving or operating machinery. Do not drive if you feel tired or drowsy.

Temperature Regulation

No specific temperature regulation warnings mentioned.

Storage

Store Combigan below 25°C in a cool, dry place, away from moisture and sunlight. Keep the container tightly closed.

Overdose Information

If you use too much Combigan, rinse your eyes with warm water. If swallowed, contact the Poisons Information Centre at 13 11 26 or seek immediate medical attention.

Frequently Asked Questions

Combigan typically begins to lower eye pressure within a few hours after application.

Combigan is an eye drop medication and does not interact with food.

No, Combigan is not considered addictive.

Do not stop using Combigan without consulting your doctor, as this may cause a rise in eye pressure.

It is advisable to avoid alcohol while using Combigan, as it may increase drowsiness.

There is no information suggesting that Combigan causes weight gain.

Elderly patients should use Combigan with caution, especially those with dementia.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double the dose.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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