Cibinqo (Abrocitinib)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Cibinqo Used For?
Cibinqo is a medication that helps manage symptoms of moderate-to-severe atopic dermatitis in adults. It reduces inflammation and itchiness associated with this skin condition.
Primary Uses
Cibinqo is primarily used to treat adults with moderate-to-severe atopic dermatitis.
How It Works
Cibinqo works by inhibiting Janus kinase enzymes, which play a role in the inflammatory process of atopic dermatitis.
Good to know: Cibinqo is not considered addictive.
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How to Take Cibinqo
Cibinqo should be taken as prescribed by your doctor, usually once daily.
Dosage Instructions
The recommended dose is either 100 mg or 200 mg once daily, depending on your doctor's assessment. If your condition is well controlled on 200 mg, your doctor may reduce the dose to 100 mg.
What If You Miss a Dose?
If you miss a dose and it is more than 12 hours before your next dose, take it as soon as you remember. If it is less than 12 hours, skip the missed dose and take your next dose at the scheduled time.
Important: Do not take a double dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Nausea
- Vomiting
- Headache
- Dizziness
- Cold sores
- Acne
Seek immediate medical attention if you experience:
- Blood clots in the lungs, legs, or pelvis
- Shingles (painful skin rash with blisters)
- Frequent infections (fever, severe chills, sore throat)
- Increased risk of cancers
- Increased cholesterol levels
Impulse Control Issues
There may be risks of impulse control issues, such as gambling or spending problems.
Important Warnings
There are several important warnings to consider before using Cibinqo.
Who Should Not Take Cibinqo
Do not use Cibinqo if you are allergic to abrocitinib or any of its ingredients, have a serious infection, severe liver problems, or are pregnant or breastfeeding.
Medical Conditions to Discuss
Discuss with your doctor if you have heart disease, a history of blood clots, cancer, or if you smoke.
Pregnancy and Breastfeeding
Cibinqo should not be used during pregnancy or while breastfeeding. Effective contraception is recommended during treatment and for at least one month after stopping.
Elderly Patients With Dementia: Elderly patients may be at increased risk of infections and other complications.
Drug Interactions
Cibinqo may interact with other medications.
Grapefruit interaction: Grapefruit may affect how Cibinqo works.
- Fluvoxamine
- Fluconazole
- Rifampin
- Antiplatelet medicines
- Antacids (famotidine, omeprazole)
- Dabigatran
- Clopidogrel
- Digoxin
- Phenytoin
- Ciclosporin
- Other Janus kinase inhibitors
- Apalutamide
- Enzalutamide
- Efavirenz
Alcohol & Driving
Precautions should be taken when consuming alcohol or driving while on Cibinqo.
Alcohol
Be cautious with alcohol consumption while taking Cibinqo until you understand how it affects you.
Driving and Operating Machinery
Cibinqo has no significant effect on the ability to drive or operate machinery.
Storage
Store Cibinqo tablets in their original packaging in a cool, dry place below 30°C. Keep out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
Cibinqo may take several weeks to show improvements in your skin condition.
You can take Cibinqo with or without food.
Cibinqo is not considered addictive.
Do not stop taking Cibinqo suddenly without consulting your doctor.
Be cautious with alcohol consumption while taking Cibinqo.
Weight gain is not commonly reported as a side effect of Cibinqo.
Elderly patients may be at increased risk of infections and should discuss their suitability with a doctor.
If you miss a dose, take it as soon as you remember if it's more than 12 hours until your next dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.