Azilect (Rasagiline)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Azilect Used For?
Azilect is a medication that helps manage the symptoms of Parkinson's disease, a condition that affects movement due to the loss of dopamine-producing cells in the brain.
Primary Uses
Azilect is primarily used to alleviate symptoms such as shaking (tremor), muscle stiffness, and slow or unsteady movements associated with Parkinson's disease.
How It Works
Azilect increases and maintains dopamine levels in the brain, which helps reduce the symptoms of Parkinson's disease.
Good to know: Azilect is not addictive.
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How to Take Azilect
It is important to take Azilect as directed by your healthcare provider.
Dosage Instructions
The usual dosage is one 1 mg tablet taken orally once a day. It can be taken with or without food.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose. Do not take a double dose.
Important: Never double the dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- flu syndrome
- malaise
- neck pain
- indigestion
- joint pain
- depression
- eye inflammation
- abdominal pain
- accidental injury (primarily falls)
- dizziness when standing
- constipation
- vomiting
- weight loss
- difficulty moving normally
- obsessive thoughts or impulsive behavior
Seek immediate medical attention if you experience:
- skin cancer (melanoma)
- severe allergic reactions
Impulse Control Issues
Azilect may increase the risk of impulse control problems, such as compulsive gambling or spending.
Important Warnings
There are several important considerations to keep in mind while using Azilect.
Who Should Not Take Azilect
Do not use Azilect if you are allergic to rasagiline or any of its ingredients, have liver problems, or if the medicine is expired or the packaging is damaged.
Medical Conditions to Discuss
Consult your doctor if you have liver issues, smoke, or notice any unusual skin changes, as there may be an increased risk of skin cancer.
Pregnancy and Breastfeeding
Inform your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, so they can discuss the risks and benefits.
Elderly Patients With Dementia: Elderly patients, especially those with dementia, should be monitored closely while taking Azilect.
Drug Interactions
Certain medications can interact with Azilect, affecting its efficacy.
Grapefruit interaction: Grapefruit may interact with Azilect, so consult your doctor.
- monoamine oxidase inhibitors (MAOIs)
- pethidine
- SSRIs
- tricyclic antidepressants
- fluoxetine
- fluvoxamine
- dextromethorphan
- sympathomimetics (e.g., ephedrine, pseudoephedrine)
- clozapine
Alcohol & Driving
Caution is advised when consuming alcohol or operating vehicles while on Azilect.
Alcohol
Be careful when drinking alcohol as it may increase side effects.
Driving and Operating Machinery
Avoid driving or operating machinery until you know how Azilect affects you, especially if you experience drowsiness.
Storage
Store Azilect below 25°C in its original blister pack, away from moisture, heat, and sunlight. Keep out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention by contacting your doctor or the Poisons Information Centre at 13 11 26.
Frequently Asked Questions
The onset of action may vary, and it is important to follow your doctor's guidance regarding its effects.
Yes, Azilect can be taken with or without food.
No, Azilect is not considered addictive.
Do not stop taking Azilect without consulting your doctor, as it may worsen your symptoms.
Be cautious with alcohol consumption, as it may increase side effects.
Weight changes are not commonly reported, but consult your doctor if you have concerns.
Elderly patients should be monitored closely while taking Azilect, especially those with dementia.
If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.