Avapro HCT (Irbesartan And Hydrochlorothiazide)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
irbesartan and hydrochlorothiazide
Drug Class
angiotensin-II receptor antagonist and diuretic
Used For
treatment of high blood pressure (hypertension)
How Taken
oral tablet, usually one tablet once a day

What Is Avapro HCT Used For?

Avapro HCT is a combination medication that helps lower high blood pressure.

Primary Uses

It is primarily used to treat hypertension.

How It Works

Irbesartan blocks the action of angiotensin II, leading to widened blood vessels, while hydrochlorothiazide increases urine output to lower blood pressure.

Good to know: Avapro HCT is not considered addictive.

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How to Take Avapro HCT

Follow your doctor's instructions on how to take Avapro HCT.

Dosage Instructions

The usual dosage is one tablet daily, taken with a glass of water, at the same time each day.

What If You Miss a Dose?

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up.

Important: Never take a double dose to make up for a missed one.

Available Tablet Strengths

150mg/12.5mg
150mg/12.5mg Tablet Peach, Oval • 2875
300mg/12.5mg
300mg/12.5mg Tablet Peach, Oval • 2876
300mg/25mg
300mg/25mg Tablet Pink, Oval • 2788

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • headache
  • dizziness or light-headedness
  • unusual tiredness
  • stomach pain
  • nausea and/or vomiting
  • sexual problems

Seek immediate medical attention if you experience:

  • swelling of the face, lips, tongue, or throat
  • severe skin reactions (hives)
  • difficulty breathing
  • muscle pain or weakness
  • changes in heart rhythm
  • vision disturbances
  • kidney issues
  • liver problems
  • jaundice
  • acute respiratory distress

Impulse Control Issues

There is no specific mention of impulse control issues related to Avapro HCT.

Important Warnings

There are important considerations to keep in mind when taking Avapro HCT.

Who Should Not Take Avapro HCT

Do not take if allergic to irbesartan, hydrochlorothiazide, or sulfonamide drugs, if pregnant, breastfeeding, or if you have certain kidney or diabetes conditions.

Medical Conditions to Discuss

Discuss any history of kidney problems, heart issues, liver problems, diabetes, gout, or electrolyte imbalances with your doctor.

Pregnancy and Breastfeeding

Do not take Avapro HCT if you are pregnant or planning to become pregnant. Avoid if breastfeeding.

Elderly Patients With Dementia: Elderly patients, especially those with dementia, should use caution.

Drug Interactions

Certain medications may interact with Avapro HCT.

Grapefruit interaction: Grapefruit may affect how Avapro HCT works.

  • other high blood pressure medications
  • other diuretics
  • lithium
  • potassium supplements
  • non-steroidal anti-inflammatory drugs (NSAIDs)
  • alcohol
  • sleeping pills
  • strong pain medications
  • diabetes medications
  • corticosteroids
  • medications for cancer
  • anticholinergic medications
  • carbamazepine

Alcohol & Driving

Be cautious with alcohol consumption and when driving while taking Avapro HCT.

Alcohol

Drinking alcohol may increase dizziness or light-headedness.

Driving and Operating Machinery

Dizziness may occur; avoid driving until you know how Avapro HCT affects you.

Temperature Regulation

Ensure adequate hydration during exercise and hot weather to avoid fainting.

Storage

Store Avapro HCT in a cool, dry place below 25°C, and keep it out of reach of children.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Symptoms may include dizziness or light-headedness.

Frequently Asked Questions

The full blood pressure-lowering effect is typically reached within 6 to 8 weeks of starting treatment.

It does not matter whether you take Avapro HCT before or after food.

No, Avapro HCT is not considered addictive.

Do not stop taking Avapro HCT without consulting your doctor, as it may affect your blood pressure.

Drinking alcohol may worsen dizziness or light-headedness.

There is no specific mention of weight gain as a side effect of Avapro HCT.

Elderly patients should use caution, especially those with dementia.

If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not double up.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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