Arava (Leflunomide)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Arava Used For?
Arava is an immunosuppressive medication that helps reduce the activity of the immune system. It is primarily used to treat rheumatoid arthritis and psoriatic arthritis.
Primary Uses
Arava is used to manage rheumatoid arthritis and psoriatic arthritis, helping to alleviate symptoms such as joint pain, swelling, and stiffness.
How It Works
Arava works by selectively inhibiting the production of lymphocytes, which are white blood cells involved in the inflammatory response that leads to joint damage.
Good to know: Arava is not considered addictive.
Continue Reading
Sign in to access the complete medication guide including dosage, side effects, warnings, and more.
How to Take Arava
Follow your doctor's instructions on how to take Arava. It is important to take it consistently for the best results.
Dosage Instructions
The typical starting dose is 100 mg per day for the first three days, followed by a maintenance dose of either 10 mg or 20 mg daily. Swallow the tablets whole with a full glass of water, and you can take them with or without food.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not take a double dose.
Important: Never take more than the prescribed dose unless directed by your doctor.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- diarrhea
- nausea and vomiting
- abdominal pain
- weight loss
- rashes
- itchy skin
- hair loss
- unusual tiredness or weakness
Seek immediate medical attention if you experience:
- fever
- severe upper stomach pain
- severe skin rash or sores in the mouth
- pale skin or increased infections
- cough or trouble breathing
- skin ulcers
- allergic reactions
Important Warnings
There are several important warnings to consider before using Arava.
Who Should Not Take Arava
Do not use Arava if you have had an allergic reaction to leflunomide or teriflunomide, are pregnant or planning to become pregnant, are not using reliable birth control, or are breastfeeding.
Medical Conditions to Discuss
Consult your doctor if you have liver disease, kidney problems, chronic infections, or any conditions that may lower your immune response.
Pregnancy and Breastfeeding
Arava should not be taken during pregnancy or while breastfeeding, as it may harm the developing baby. Women of childbearing potential must use reliable contraception while on this medication.
Drug Interactions
Some medications may interact with Arava and affect its efficacy.
- warfarin (used for blood clots)
- diabetes medications
- epilepsy medications
- tuberculosis treatments
- cholesterol-lowering medications
Alcohol & Driving
Be cautious with alcohol consumption while taking Arava, as it may enhance certain side effects.
Alcohol
Minimize alcohol intake while on Arava, and inform your doctor if you consume alcohol.
Driving and Operating Machinery
If you experience dizziness or fatigue, avoid driving or operating heavy machinery.
Storage
Store Arava in a cool, dry place below 25°C, away from moisture, heat, and sunlight. Keep it out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Contact your doctor or call the Poisons Information Centre at 13 11 26 in Australia or 0800 764 766 in New Zealand.
Frequently Asked Questions
It may take several weeks to notice the full benefits of Arava in managing your symptoms.
Yes, you can take Arava with or without food.
No, Arava is not considered addictive.
Do not stop taking Arava without consulting your doctor, as it may worsen your condition.
It is recommended to minimize alcohol intake while on Arava.
Weight loss has been reported as a side effect, but weight gain is not specifically mentioned.
Consult your doctor regarding the safety of Arava for elderly patients, especially those with existing health conditions.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.