Apretude Tablets (Cabotegravir)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Apretude Tablets Used For?
Apretude Tablets are used as a preventive measure against HIV infection in individuals who are at risk. It is part of a strategy known as pre-exposure prophylaxis (PrEP).
Primary Uses
Apretude is primarily used to lower the risk of acquiring HIV in individuals who are HIV negative.
How It Works
Apretude contains cabotegravir, which works by inhibiting the integrase enzyme, preventing HIV from replicating in the body.
Good to know: Apretude is not addictive.
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How to Take Apretude Tablets
It is important to take Apretude Tablets as directed by your healthcare provider to ensure maximum effectiveness.
Dosage Instructions
The recommended dosage for adults and adolescents weighing 35 kg or more is one 30 mg tablet taken once daily. If you need to take an antacid, do so at least 2 hours before or 4 hours after taking Apretude.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. Do not take a double dose to make up for the missed one.
Important: Do not double dose if you miss a dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- diarrhoea
- fever
Seek immediate medical attention if you experience:
- allergic reactions
- liver problems
- Stevens-Johnson syndrome (SJS)
- toxic epidermal necrolysis (TEN)
Important Warnings
There are several important considerations to keep in mind while taking Apretude.
Who Should Not Take Apretude Tablets
Do not take Apretude if you have a known allergy to cabotegravir or any of its ingredients, or if you have not been tested for HIV and confirmed negative.
Medical Conditions to Discuss
Inform your doctor if you have any other medical conditions, especially liver problems, as this may affect your treatment.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, plan to become pregnant, or are breastfeeding, as the effects on the baby are not fully known.
Drug Interactions
Certain medications may interact with Apretude and affect how it works.
- rifampicin
- rifapentine
- phenytoin
- phenobarbital
- carbamazepine
- oxcarbazepine
Alcohol & Driving
Be cautious when consuming alcohol and operating vehicles or machinery while taking Apretude.
Alcohol
Consult your doctor about alcohol consumption while on Apretude.
Driving and Operating Machinery
Apretude may cause dizziness; do not drive or operate heavy machinery if you feel affected.
Storage
Store Apretude Tablets in a cool, dry place below 30°C, and keep them in their original bottle until you are ready to take them.
Overdose Information
If you suspect an overdose, seek immediate medical attention by contacting your doctor or going to the nearest emergency department.
Frequently Asked Questions
Apretude is typically taken for at least one month before transitioning to injections, allowing your doctor to assess its effectiveness.
Apretude can be taken with or without food.
No, Apretude is not considered addictive.
Do not stop taking Apretude without consulting your doctor, as this may increase your risk of HIV infection.
Consult your doctor regarding alcohol consumption while on Apretude.
Weight gain is listed as an uncommon side effect; speak to your doctor if you have concerns.
Elderly patients should consult their doctor to ensure Apretude is safe for them.
If you miss a dose, take it as soon as you remember, but do not double dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.