Apretude Injection (Cabotegravir)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Apretude Injection Used For?
Apretude Injection is a medication that helps lower the risk of acquiring HIV infection in individuals who weigh 35 kg or more. It is classified as a pre-exposure prophylaxis (PrEP).
Primary Uses
Apretude is primarily used for pre-exposure prophylaxis (PrEP) to prevent HIV infection.
How It Works
Apretude works by inhibiting the integrase enzyme, which is essential for the HIV virus to replicate.
Good to know: Apretude is not addictive.
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How to Take Apretude Injection
Apretude is administered as an injection into the muscle of the buttock by a healthcare professional.
Dosage Instructions
Apretude is given as a single injection of 3 mL (600 mg) every 2 months. The first two injections should be one month apart.
What If You Miss a Dose?
If you miss an injection, contact your doctor immediately to reschedule. It is crucial to maintain your injection schedule to effectively reduce the risk of HIV.
Important: Do not double dose if you miss an injection.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- headache
- diarrhoea
- injection site reactions
- fever
Seek immediate medical attention if you experience:
- allergic reactions
- liver problems
- Stevens-Johnson syndrome (SJS)
- toxic epidermal necrolysis (TEN)
Important Warnings
There are specific precautions and contraindications associated with Apretude Injection.
Who Should Not Take Apretude Injection
Do not use Apretude if you are allergic to cabotegravir or any of its ingredients. Ensure you have a recent negative HIV test before starting treatment.
Medical Conditions to Discuss
Inform your doctor about any other medical conditions, especially liver problems, as they may require closer monitoring.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Apretude may remain in your system for up to 12 months after the last injection.
Drug Interactions
Certain medications may interact with Apretude and affect its efficacy.
- rifampicin
- rifapentine
- phenytoin
- phenobarbital
- carbamazepine
- oxcarbazepine
Alcohol & Driving
Caution is advised when driving or operating machinery while using Apretude.
Alcohol
There are no specific warnings about alcohol consumption with Apretude, but it is advisable to consult your doctor.
Driving and Operating Machinery
Apretude may cause dizziness; do not drive or operate machinery until you know how it affects you.
Storage
Store Apretude injection in its original packaging below 30°C until it is time for use.
Overdose Information
Overdose is unlikely as Apretude is administered by a healthcare professional. If you suspect an overdose, inform your doctor or nurse immediately.
Frequently Asked Questions
Apretude Injection starts working to reduce the risk of HIV infection shortly after administration, but it is important to maintain the injection schedule.
There are no specific dietary restrictions mentioned for Apretude Injection.
No, Apretude Injection is not considered addictive.
If you stop Apretude, you may need to take other precautions to reduce the risk of HIV infection as the medication can remain in your system for up to a year.
Consult your doctor regarding alcohol consumption while on Apretude.
Weight gain is not listed as a common side effect of Apretude Injection.
Elderly patients should discuss their health status with their doctor before starting Apretude Injection.
Contact your doctor immediately to reschedule your injection if you miss a dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.