Adcetris (Brentuximab Vedotin)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Adcetris Used For?
Adcetris is a medication designed to treat specific types of lymphomas, particularly Hodgkin Lymphoma and other T-Cell Lymphomas.
Primary Uses
Adcetris is used for patients with Hodgkin Lymphoma who have not been treated before, for those whose Hodgkin Lymphoma has returned or not responded to prior treatments, and to reduce the risk of recurrence after a stem cell transplant. It is also used for cutaneous T-Cell Lymphoma after prior treatment and for untreated Peripheral T-Cell Lymphoma.
How It Works
Adcetris combines a monoclonal antibody with a substance that targets and kills cancer cells, differentiating it from traditional chemotherapy that affects both cancerous and healthy rapidly dividing cells.
Good to know: Adcetris is not addictive.
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How to Take Adcetris
Adcetris is administered by a healthcare professional through an intravenous infusion.
Dosage Instructions
The typical dose is 1.8 mg/kg administered every 3 weeks when given alone. For Hodgkin Lymphoma, it may be combined with other chemotherapy agents, with doses adjusted based on individual health factors.
What If You Miss a Dose?
If you miss an appointment for your infusion, reschedule as soon as possible.
Important: Do not double the dose if you miss an appointment.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- upper respiratory tract infection
- pneumonia
- back pain
- constipation
- nausea
- vomiting
- fatigue
- frequent urination
- increased thirst
- changes in appetite
- weight loss
- irritability
- unusual bleeding or bruising
- headaches
- dizziness
- itching
- hair loss or thinning
- muscle pain
- joint pain
- skin redness or pain at infusion site
Seek immediate medical attention if you experience:
- confusion or trouble thinking clearly
- memory loss
- blurred or loss of vision
- decreased strength or sensation in limbs
- new or worsening shortness of breath or cough
- decreased urination
- heart rhythm disturbances
- severe skin reactions
- swelling of face or throat
- severe abdominal pain
- jaundice
Important Warnings
There are specific warnings associated with the use of Adcetris that patients should be aware of.
Who Should Not Take Adcetris
Do not use Adcetris if you have had an allergic reaction to brentuximab vedotin or any of its ingredients, or if you are currently taking bleomycin.
Medical Conditions to Discuss
Discuss any allergies, infections, kidney or liver issues, and other medications you are taking with your doctor.
Pregnancy and Breastfeeding
Women must use effective contraception during treatment and for 6 months after. Men are advised to store sperm before treatment and avoid fathering a child during and for 6 months after treatment.
Drug Interactions
Certain medications may interact with Adcetris, affecting its efficacy.
- ketoconazole
- itraconazole
Alcohol & Driving
Be cautious with alcohol and driving while on Adcetris, as it may cause dizziness.
Alcohol
Consult your doctor about alcohol consumption while taking Adcetris.
Driving and Operating Machinery
Avoid driving or operating machinery if you feel dizzy.
Storage
Store the unopened vial in a refrigerator at 2-8 degrees Celsius. Do not freeze and keep it in the original carton to protect from light.
Overdose Information
Overdose is unlikely as Adcetris is administered by a healthcare professional. If you suspect an overdose, seek immediate medical attention.
Frequently Asked Questions
The time it takes for Adcetris to show effects can vary by individual and condition.
There are no specific dietary restrictions mentioned for Adcetris.
No, Adcetris is not considered addictive.
Do not stop taking Adcetris without consulting your doctor first.
Consult your doctor regarding alcohol consumption while on Adcetris.
Weight changes may occur; consult your doctor if you have concerns.
Elderly patients should discuss their health conditions with their doctor before starting Adcetris.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.