Adacel (Diphtheria Toxoid, Tetanus Toxoid, Pertactin, Pertussis Filamentous Haemagglutinin, Pertussis Fimbriae 2 + 3, And Pertussis Toxoid)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
Diphtheria toxoid, Tetanus toxoid, Pertactin, Pertussis filamentous haemagglutinin, Pertussis fimbriae 2 + 3, and Pertussis toxoid
Drug Class
Vaccine
Used For
Prevention of whooping cough (pertussis), tetanus and diphtheria
How Taken
Single injection (0.5mL) into upper arm muscle

What Is Adacel Used For?

Adacel is a vaccine that helps protect against three serious diseases: whooping cough (pertussis), tetanus, and diphtheria. It’s designed as a booster shot for people who have already received their childhood immunizations.

Primary Uses

Adacel is used as a booster vaccine for people aged 10 years and older who have previously received childhood immunization against whooping cough, tetanus, and diphtheria. When given during pregnancy, it helps protect newborn babies from whooping cough during their first few months of life by passing antibodies from mother to baby.

How It Works

Adacel works by causing your body to produce its own protection against whooping cough, tetanus, and diphtheria. It does this by making substances called antibodies in your blood, which fight the bacteria and toxins that cause these diseases. If you come into contact with these bacteria and toxins after vaccination, your body is usually ready to destroy them. It typically takes several weeks after vaccination to develop full protection.

Good to know: The vaccine will not give you any of these diseases. While 100% protection cannot be guaranteed, most people will produce enough antibodies against these diseases.

How to Take Adacel

Adacel is given as a single injection by a healthcare professional. You don’t need to do anything special to prepare for the vaccination.

Dosage Instructions

The dose of Adacel is a single dose of 0.5mL given as an injection, usually into your upper arm muscle by a doctor or nurse. Adacel should not be injected directly into the veins. The vaccine is generally given whenever a booster dose of whooping cough, tetanus and diphtheria vaccine is required.

What If You Miss a Dose?

Since Adacel is typically given as a single booster dose, missing a dose is not usually applicable. If you have concerns about your vaccination schedule, speak with your healthcare provider.

Important: Overdose is most unlikely because your doctor or nurse gives the injections. If you have any concerns, ask your doctor.

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Local reaction around injection site (redness, pain, discomfort, swelling, hard lumps)
  • Headaches
  • Tiredness, weakness or fatigue
  • Fever
  • Chills
  • Soreness, aching muscles, muscle tenderness or weakness
  • Joint pain or joint swelling
  • Nausea and vomiting
  • Diarrhea
  • Loss of appetite
  • Large injection site reactions and extensive limb swelling
  • Injection site bruising, abscess
  • Small lump in the area where vaccine was injected

Seek immediate medical attention if you experience:

  • Sudden severe allergic reactions (anaphylactic reaction) with rash, low blood pressure, swelling of face/lips/tongue, shortness of breath, wheezing
  • Neurological disorders causing confusion, numbness, tingling, pain and weakness of limbs, loss of balance, loss of reflexes, paralysis (Guillain-Barre syndrome, brachial neuritis, myelitis)
  • Decreased feeling or sensitivity, especially in skin
  • Fainting
  • Convulsion
  • Drooping eyelid and sagging muscles on one side of face (facial palsy)
  • Tingling or numbness of hands or feet
  • Itching or hives on skin
  • Weakness and pain in muscles (myositis)
  • Inflammation of heart muscle with shortness of breath, chest pain and irregular heartbeat (myocarditis)

Important Warnings

There are certain situations where Adacel should not be used, and medical conditions that need to be discussed with your doctor before vaccination.

Who Should Not Take Adacel

Do not use Adacel if you: are allergic to the active ingredients or any ingredients listed; have a history of severe allergic reaction to a previous dose of this vaccine or another vaccine for pertussis, tetanus and diphtheria; had serious brain disease (encephalopathy) without an apparent cause within 7 days of a previous pertussis, tetanus or diphtheria vaccination; have moderate or high temperature and/or acute illness. Adacel is not recommended for children under 10 years.

Medical Conditions to Discuss

Check with your doctor if you have: moderate or high temperature and/or acute illness; lowered immunity due to diseases such as blood disorders, kidney disease requiring dialysis, HIV/AIDS or cancer; lowered immunity due to treatment with medicines; Guillain-Barre syndrome after being given a vaccine containing tetanus toxoid; undiagnosed brain illness or uncontrolled epilepsy; bleeding disorder; allergy to latex.

Pregnancy and Breastfeeding

Check with your doctor if you are pregnant or intend to become pregnant. Your doctor will discuss the possible risks and benefits of having Adacel during pregnancy. Adacel may be given during pregnancy for prevention of pertussis in young infants. Talk to your doctor if you are breastfeeding or intend to breastfeed, as your doctor will discuss the possible risks and benefits.

Drug Interactions

Some medicines may interfere with Adacel and affect how it works. Always tell your healthcare provider about all medications you’re taking.

  • Medicines that lower immunity
  • Other vaccines (your doctor will advise if Adacel can be given with another vaccine)
  • Any medicines, vitamins or supplements bought without prescription

Alcohol & Driving

The source material does not provide specific information about alcohol consumption or driving restrictions with Adacel vaccination.

Storage

Adacel is usually stored in the doctor’s surgery or clinic. However, if you need to store Adacel: Keep it in the original pack until it’s time to be given. Store in the refrigerator between 2°C and 8°C. If stored out of the refrigerator at room temperature, it can be used for up to 72 hours after it was last refrigerated. If stored out of the refrigerator for longer than 72 hours, it should be discarded. Do not freeze Adacel – freezing destroys the vaccine. Do not use after the expiry date. Do not use if packaging is torn or shows signs of tampering. Keep where young children cannot reach it.

Overdose Information

Overdose is most unlikely because your doctor or nurse gives the injections. If you have any concerns, ask your doctor. Call your doctor straight away if you do not feel well after having Adacel.

Frequently Asked Questions

It usually takes several weeks after vaccination to develop protection against whooping cough, tetanus, and diphtheria. Most people will produce enough antibodies against these diseases during this time.

Yes, Adacel may be given during pregnancy for prevention of pertussis in young infants. Your doctor will discuss the possible risks and benefits of having Adacel during pregnancy. The vaccine allows antibodies to be passed to the baby in the womb to protect them from whooping cough during their first few months of life.

Call your doctor straight away if you do not feel well after having Adacel. Most side effects are minor and temporary, but some may need medical attention. Seek immediate medical help if you experience severe allergic reactions, neurological symptoms, or other serious side effects.

Your doctor will advise you if Adacel can be given with another vaccine. Always tell your healthcare provider about any other vaccines you’re planning to receive.

You should not receive Adacel if you’re allergic to its ingredients, have had severe allergic reactions to previous doses, experienced serious brain disease within 7 days of a previous pertussis/tetanus/diphtheria vaccination, have moderate to high fever or acute illness, or are under 10 years old.

Adacel helps protect against three serious diseases: whooping cough (pertussis), tetanus, and diphtheria. It’s used as a booster for people aged 10 years and older who have previously received childhood immunization.

No, the vaccine will not give you whooping cough, tetanus, or diphtheria. While 100% protection cannot be guaranteed with any vaccine, most people will develop adequate protection against these diseases.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.