Abstral sublingual tablets (Fentanyl (As Citrate))
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Abstral sublingual tablets Used For?
Abstral is a potent pain relief medication specifically designed for adults experiencing breakthrough cancer pain while on a stable dose of opioid therapy for their ongoing cancer pain.
Primary Uses
It is primarily used to manage sudden episodes of intense pain that occur despite ongoing cancer pain management.
How It Works
Abstral works by blocking pain signals in the brain, providing rapid relief for breakthrough pain.
Good to know: Abstral is effective for managing breakthrough pain when used as directed.
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How to Take Abstral sublingual tablets
To use Abstral effectively, follow your doctor's instructions carefully regarding dosage and administration.
Dosage Instructions
Start with a dose of 100 micrograms. If pain relief is not achieved within 30 minutes, a second 100 microgram tablet may be taken. Do not exceed two doses for each pain episode and wait at least 2 hours before taking more.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember, but do not double up on doses. If it's almost time for your next dose, skip the missed dose.
Important: Never take more than the prescribed dose for breakthrough pain.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- nausea
- drowsiness
- vomiting
Seek immediate medical attention if you experience:
- shortness of breath
- wheezing
- difficulty breathing
- fast or slow heartbeat
- dizziness or light-headedness
- extreme mood swings
- blurred vision
- swelling of the face or lips
- skin rashes
Impulse Control Issues
Abstral may lead to issues with impulse control, such as increased risk of addiction.
Important Warnings
Abstral carries significant risks and should be used with caution.
Who Should Not Take Abstral sublingual tablets
Do not use Abstral if you have a known allergy to fentanyl or any of its ingredients, are not already on opioid therapy, or have breathing difficulties.
Medical Conditions to Discuss
Inform your doctor if you have asthma, COPD, heart problems, liver or kidney issues, or a history of substance abuse.
Pregnancy and Breastfeeding
Consult your doctor if you are pregnant or breastfeeding, as fentanyl can harm newborns and may pass into breast milk.
Elderly Patients With Dementia: Elderly patients, especially those with dementia, may be at higher risk for adverse effects.
Drug Interactions
Certain medications can interact with Abstral and affect its efficacy.
Grapefruit interaction: Avoid grapefruit juice as it may increase side effects.
- antibiotics (e.g., erythromycin, rifampicin)
- antifungals (e.g., ketoconazole, itraconazole)
- HIV medications (e.g., ritonavir)
- anticonvulsants (e.g., gabapentin, pregabalin)
- muscle relaxants
- sedatives (e.g., benzodiazepines)
- alcohol
Alcohol & Driving
Caution is advised regarding alcohol consumption and operating vehicles while on Abstral.
Alcohol
Do not drink alcohol while taking Abstral, as it can enhance drowsiness and dizziness.
Driving and Operating Machinery
Avoid driving or using machinery while taking Abstral due to potential impairment.
Storage
Store Abstral in a cool, dry place below 25°C, away from moisture and heat, and out of reach of children.
Overdose Information
In case of overdose, seek immediate medical help. Symptoms may include slow or difficult breathing, extreme drowsiness, and fainting.
Frequently Asked Questions
Abstral typically begins to relieve breakthrough pain within 30 minutes after administration.
It is recommended to avoid eating or drinking until the tablet has completely dissolved under your tongue.
Yes, Abstral has the potential for addiction and should be used only as prescribed.
Stopping Abstral suddenly may lead to withdrawal symptoms, and you should consult your doctor before discontinuing.
No, alcohol should be avoided as it can increase the risk of severe side effects.
Weight gain is not specifically mentioned as a side effect of Abstral.
Elderly patients should use Abstral with caution, especially if they have dementia or other cognitive impairments.
If you miss a dose, take it as soon as you remember, but do not double up on doses.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.