Abraxane (Paclitaxel)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
paclitaxel
Drug Class
antineoplastic or cytotoxic medicines
Used For
treating breast cancer, lung cancer, and pancreatic cancer
How Taken
administered as an infusion into a vein, typically every three weeks or weekly depending on the condition

What Is Abraxane Used For?

Abraxane is a chemotherapy medication that contains paclitaxel, used primarily to treat various types of cancer.

Primary Uses

It is used to treat breast cancer, lung cancer, and pancreatic cancer.

How It Works

Abraxane works by killing cancer cells and preventing them from multiplying.

Good to know: Abraxane is not considered addictive.

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How to Take Abraxane

Abraxane is given by a healthcare professional as an infusion, and the dosage will be determined by your doctor based on various factors.

Dosage Instructions

The dosage of Abraxane depends on your medical condition, weight, kidney function, and other chemotherapy medications you may be receiving.

What If You Miss a Dose?

It is crucial to keep all appointments for your Abraxane infusion. If you miss an appointment, consult your doctor for rescheduling.

Important: Never double dose if you miss an appointment.

Available Tablet Strengths

100mg
100mg Tablet White to yellow, Solid powder cake • AUST R 133500
250mg
250mg Tablet White to yellow, Solid powder cake • AUST R 297973

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • nausea
  • vomiting
  • hair loss
  • weakness and tiredness
  • pain in joints or muscles
  • decreased appetite
  • diarrhea
  • constipation

Seek immediate medical attention if you experience:

  • shortness of breath or difficulty breathing
  • swelling of the face, lips, or tongue
  • severe rash or hives
  • extreme weakness or tiredness
  • seizures
  • irregular heartbeats
  • chest pain
  • yellowing of skin or eyes
  • unusual bleeding or bruising
  • signs of infection (fever, sore throat)

Impulse Control Issues

There is no specific mention of impulse control issues related to Abraxane.

Important Warnings

There are several important warnings to consider before using Abraxane.

Who Should Not Take Abraxane

Do not use Abraxane if you are allergic to paclitaxel or human albumin, have a very low white blood cell count, are pregnant, or are breastfeeding.

Medical Conditions to Discuss

Discuss with your doctor if you have kidney disease, liver disease, heart problems, blood disorders, nerve diseases, or infections.

Pregnancy and Breastfeeding

Abraxane is not recommended during pregnancy due to potential risks to the fetus. It can also pass into breast milk, potentially affecting a nursing baby.

Elderly Patients With Dementia: Special caution is advised for elderly patients, particularly those with dementia.

Drug Interactions

Certain medications may interact with Abraxane, affecting its efficacy.

Grapefruit interaction: Consult your doctor about potential grapefruit interactions.

  • antibiotics (e.g., erythromycin, rifampicin)
  • antifungal medications (e.g., ketoconazole)
  • antidepressants (e.g., fluoxetine)
  • seizure medications (e.g., carbamazepine, phenytoin)
  • cholesterol-lowering medications (e.g., gemfibrozil)
  • stomach ulcer medications (e.g., cimetidine)
  • HIV medications (e.g., ritonavir, saquinavir)

Alcohol & Driving

Be cautious with alcohol consumption and operating vehicles or machinery while on Abraxane.

Alcohol

Consult your doctor regarding alcohol consumption while on this medication.

Driving and Operating Machinery

Some patients may experience dizziness or fatigue. If this occurs, avoid driving or using machinery.

Storage

Store Abraxane in a cool, dry place, protected from light, and below 25°C.

Overdose Information

If you suspect an overdose, seek immediate medical attention. Symptoms may include severe side effects.

Frequently Asked Questions

The effects of Abraxane may take some time to become noticeable, and your doctor will monitor your progress.

Abraxane is administered as an infusion and does not have specific food interactions.

Abraxane is not considered addictive.

Consult your doctor before stopping Abraxane, as it may affect your treatment plan.

It's best to consult your doctor regarding alcohol consumption during treatment.

Weight changes are not specifically mentioned, but discuss any concerns with your doctor.

Elderly patients should use Abraxane with caution, especially those with dementia.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.

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