Panadol Allergy Sinus (Paracetamol 500Mg, Pseudoephedrine Hydrochloride 30Mg, Chlorphenamine Maleate 2Mg)

Complete patient guide for uses, dosage, side effects, and safety information

Prescription Required

Quick Facts

Generic Name
Paracetamol 500mg, Pseudoephedrine Hydrochloride 30mg, Chlorphenamine Maleate 2mg
Drug Class
Analgesic, Decongestant, and Antihistamine combination
Used For
Temporary relief of sinusitis symptoms, nasal congestion, and allergic symptoms
How Taken
Oral tablets, 2 tablets every 6 hours as needed

What Is Panadol Allergy Sinus Used For?

Panadol Allergy Sinus is a combination medication that contains three active ingredients working together to provide relief from multiple symptoms.

Primary Uses

This medication is used for the temporary relief of sinusitis symptoms, nasal congestion, and allergic symptoms such as runny nose, sneezing, itchy and watery eyes.

How It Works

Paracetamol stops pain messages from reaching the brain and reduces fever. Pseudoephedrine hydrochloride reduces congestion in the upper respiratory tract, nose, nasal passages and sinuses, making breathing easier. Chlorphenamine maleate is an antihistamine that reduces allergic symptoms by preventing the effects of histamine, which the body produces in response to allergens.

How to Take Panadol Allergy Sinus

Always follow the directions carefully and use the smallest dose needed to treat your symptoms for the shortest time necessary.

Dosage Instructions

Adults and children 12 years and over: Take 2 tablets every 6 hours as necessary. Do not take more than 8 tablets in 24 hours. Do not take more frequently than every 6 hours. Swallow with water or other fluid. Do not use in children under 12 years. Adults should only take for a few days at a time unless your doctor tells you otherwise. Children 12-17 years should only be given this medication for up to 48 hours unless a doctor advises longer use.

Never Exceed Dose: Do not take more than the recommended dose as it may cause serious harm to your liver.

Available Tablet Strengths

Paracetamol 500mg + Pseudoephedrine HCl 30mg + Chlorphenamine Maleate 2mg
Paracetamol 500mg + Pseudoephedrine HCl 30mg + Chlorphenamine Maleate 2mg Tablet White, Capsule-shaped with flat edges • PANADOL on one face and C&F C&F (upside down) on the other

Side Effects

Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.

Common Side Effects

These side effects occur relatively frequently and usually don’t require emergency care:

  • Nervousness
  • Difficulty sleeping
  • Dizziness
  • Dry mouth, nose or throat
  • Fear or anxiety
  • Headache
  • Tremor
  • Increased blood pressure
  • Nausea or stomach upset or vomiting
  • Drowsiness or sedation
  • Agitation
  • Restlessness
  • Excitability
  • Constipation
  • Twitching or jerking muscles
  • Fatigue
  • Blurred vision
  • Difficulty concentrating
  • Lack of coordination
  • Hallucinations (particularly in children)

Seek immediate medical attention if you experience:

  • Sudden chest pain or discomfort
  • Shortness of breath
  • Wheezing or difficulty breathing
  • Swelling of face, lips, tongue or other body parts
  • Allergic skin reactions like rash, peeling, itching or hives
  • Mouth ulcers
  • Unexplained bruising or bleeding
  • Symptoms of metabolic acidosis including serious breathing difficulties with deep rapid breathing, drowsiness, nausea, vomiting and loss of appetite
  • Rapid or irregular heartbeat
  • Trouble urinating or urinary retention or painful urination
  • Sudden and severe headache or thunderclap headache with or without nausea, vomiting, confusion, seizures and/or visual disturbances
  • Sudden abdominal pain or blood in stool
  • Seizures (fits)

Important Warnings

There are several important conditions and situations where this medication should not be used or requires special caution.

Who Should Not Take Panadol Allergy Sinus

Do not use if you are allergic to paracetamol, pseudoephedrine, chlorphenamine maleate, or any ingredients; taking other paracetamol-containing medicines; taking other cold/flu medicines, tricyclic antidepressants, amphetamines, or appetite suppressants; have very high or uncontrolled blood pressure; have heart disease or blood vessel problems; have severe kidney disease or kidney failure; have taken MAO inhibitors in the last 14 days; are taking furazolidone or linezolid antibiotics; have stomach or duodenal ulcers; have bladder problems; or if the product is expired or damaged. This medicine should not be given to elderly patients with confusion.

Medical Conditions to Discuss

Check with your doctor or pharmacist if you have liver or kidney disease, diabetes, high blood pressure, heart problems, overactive thyroid, glaucoma, poor blood circulation, adrenal gland tumors, psychosis, upcoming surgery, epilepsy, prostate problems, irregular heartbeat, asthma or respiratory problems, are underweight or malnourished, regularly drink alcohol, are over 60 years old, have severe illness or infection, or are a chronic heavy alcohol user.

Pregnancy and Breastfeeding

Ask your doctor before use if you are pregnant, intend to become pregnant, or are breastfeeding.

Elderly Patients With Confusion: Carers should be aware that this medicine should not be given to elderly patients with confusion.

Metabolic Acidosis Risk: If you have severe illness, severe infection, are severely malnourished or are a chronic heavy alcohol user, you may be at increased risk of metabolic acidosis. Signs include deep, rapid, difficult breathing, nausea, vomiting, loss of appetite, and drowsiness. Contact your doctor immediately if you experience these symptoms.

Drug Interactions

Many medications can interact with Panadol Allergy Sinus. Always tell your doctor or pharmacist about all medicines you are taking.

  • Warfarin or similar blood thinners
  • Metoclopramide for nausea and vomiting
  • Anti-epilepsy medicines like phenytoin
  • Chloramphenicol antibiotic
  • Alcohol
  • Probenecid for gout
  • Cholestyramine for high cholesterol
  • Flucloxacillin antibiotic
  • Pain relievers, sedatives, and sleep aids
  • MAO inhibitors and tricyclic antidepressants
  • Heart medications like digoxin
  • Blood pressure medications like beta-blockers
  • Urinary tract infection medicines
  • Behavioral disorder medications
  • Phenylephrine and other decongestants
  • Appetite suppressants
  • Opioid pain medications
  • Furazolidone or linezolid antibiotics
  • Migraine medications like ergotamine and methysergide

Alcohol & Driving

This medication can affect your ability to drive safely and should not be combined with alcohol.

Alcohol

Do not drink alcohol while taking Panadol Allergy Sinus.

Driving and Operating Machinery

Be careful before you drive or use any machines or tools until you know how Panadol Allergy Sinus affects you. This medicine may cause dizziness, sleepiness or blurred vision in some people. If affected, do not drive or operate machinery.

Storage

Store your medicine in a cool dry place where the temperature stays below 30°C. Keep away from moisture, heat or sunlight. Do not store in the bathroom, near a sink, in the car or on window sills. Keep in the original pack until time to take it. Keep out of sight and reach of children. A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Overdose Information

If you think you have taken too much Panadol Allergy Sinus, you may need urgent medical attention. Immediately phone the Poisons Information Centre (13 11 26 for Australia, 0800 764 766 for NZ) or go to the Emergency Department at your nearest hospital. Do this even if there are no signs of discomfort or poisoning because of the risk of delayed, serious liver damage or failure if left untreated.

Frequently Asked Questions

The medication contains three active ingredients that work at different rates. The paracetamol component typically begins working within 30-60 minutes for pain and fever relief, while the decongestant and antihistamine effects may take a similar timeframe to provide relief from congestion and allergic symptoms.

The medication should be swallowed with water or other fluid. The instructions do not specify whether it needs to be taken with or without food, so you can take it either way.

The source material does not indicate that this medication is addictive. However, it should only be used for short periods – adults should only take it for a few days at a time, and children 12-17 years should only use it for up to 48 hours unless a doctor advises otherwise.

This medication is intended for short-term use only (a few days for adults, up to 48 hours for children 12-17 years). There are no withdrawal concerns mentioned as it’s designed for temporary symptom relief rather than long-term treatment.

No, you should not drink alcohol while taking Panadol Allergy Sinus. The medication specifically warns against alcohol consumption, and alcohol is also listed as a substance that may interfere with the paracetamol component.

Patients over 60 years old have an increased possibility of unwanted effects. Additionally, this medicine should not be given to elderly patients with confusion. Elderly patients should consult with their doctor or pharmacist before use.

This medication is taken as needed for symptom relief rather than on a regular schedule. Take it when you have symptoms, but do not take doses more frequently than every 6 hours and do not exceed 8 tablets in 24 hours.

Important Disclaimer

This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.

If you think you may have a medical emergency, call your doctor or emergency services immediately.