Onureg (Azacitidine)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Onureg Used For?
Onureg is a medication that helps treat adults diagnosed with acute myeloid leukaemia (AML), a type of cancer affecting the bone marrow.
Primary Uses
Onureg is primarily used to treat acute myeloid leukaemia (AML) in adults.
How It Works
Azacitidine works by interfering with the growth of cancer cells, altering how genes are activated and reducing the production of new genetic material, which helps to kill leukaemia cells.
Good to know: Onureg is not considered addictive.
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How to Take Onureg
It is important to take Onureg exactly as prescribed by your healthcare provider.
Dosage Instructions
The recommended dosage is 300 mg taken orally once daily. Your doctor may adjust this to 200 mg daily if necessary. Onureg is taken for the first 14 days of a 28-day treatment cycle, followed by a 14-day break.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember on the same day. Do not take two doses on the same day.
Important: Never double your dose to make up for a missed dose.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Constipation
- Abdominal pain
- Infections of the nose, sinuses, and throat
- Fatigue or weakness
- Loss of appetite
- Pain in various body parts
- Stiff joints
- Back pain
Seek immediate medical attention if you experience:
- Bruising or bleeding due to low platelet count
- Fever possibly indicating an infection
- Diarrhoea or nausea
- Infection of the lungs or urinary tract
- Fatigue, irregular heartbeats, pale complexion, shortness of breath, weakness
- Fainting
- Flu-like symptoms
Important Warnings
Before using Onureg, it's essential to understand the associated risks and who should avoid this medication.
Who Should Not Take Onureg
Do not use Onureg if you are allergic to azacitidine or any of its ingredients, are pregnant, or are breastfeeding.
Medical Conditions to Discuss
Discuss any other medical conditions or medications you are taking with your doctor before starting Onureg.
Pregnancy and Breastfeeding
Onureg should not be taken during pregnancy as it may harm the unborn baby. Breastfeeding is also not recommended while using this medication.
Drug Interactions
Some medications may interact with Onureg, affecting its effectiveness or increasing side effects.
Alcohol & Driving
Caution is advised when consuming alcohol or operating machinery while taking Onureg.
Alcohol
Consult your doctor regarding alcohol consumption while on Onureg.
Driving and Operating Machinery
Onureg may cause tiredness or dizziness. Avoid driving or operating heavy machinery until you know how Onureg affects you.
Storage
Store Onureg tablets in their original packaging below 25°C, away from moisture and heat. Keep out of reach of children.
Overdose Information
If you suspect an overdose of Onureg, seek immediate medical attention. Bring the medication pack and this leaflet with you.
Frequently Asked Questions
The effectiveness of Onureg may vary, but it is typically used in cycles to manage symptoms and maintain remission.
Onureg can be taken with or without food.
No, Onureg is not considered addictive.
Do not stop taking Onureg without consulting your doctor, as it may affect your treatment.
Consult your doctor regarding alcohol consumption while on Onureg.
Weight changes are not specifically mentioned, but discuss any concerns with your doctor.
Elderly patients should consult their doctor to ensure Onureg is safe for them.
If you miss a dose, take it as soon as you remember on the same day, but do not double up on doses.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.