Omtralo (Sacubitril And Valsartan)
Complete patient guide for uses, dosage, side effects, and safety information
Quick Facts
What Is Omtralo Used For?
Omtralo is a medication that combines sacubitril and valsartan to treat heart failure in adults. It helps lower the risk of cardiovascular-related deaths and hospitalizations due to heart failure.
Primary Uses
Omtralo is primarily used to manage heart failure.
How It Works
Omtralo works by inhibiting neprilysin and blocking the effects of angiotensin-II, leading to relaxed blood vessels and reduced fluid retention.
Good to know: Omtralo is not considered addictive.
Continue Reading
Sign in to access the complete medication guide including dosage, side effects, warnings, and more.
How to Take Omtralo
Omtralo should be taken as prescribed by your doctor, typically in the morning and evening.
Dosage Instructions
The usual starting dose is one 49 mg/51 mg tablet taken twice daily. Your doctor may adjust the dosage based on your response to treatment.
What If You Miss a Dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Important: Never take a double dose to make up for a missed one.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Dizziness
- Fainting
- Light-headedness
- Cough
- Headache
- Diarrhea
- Nausea
- Stomach pain
- Tiredness
- Weakness
Seek immediate medical attention if you experience:
- Swelling of the face, lips, tongue, and/or throat
- Difficulty breathing or swallowing
- Chest pain
- Fast heartbeat
- Shortness of breath
- Swelling of the feet, ankles, or hands
- Wheezing
- Persistent cough
Important Warnings
There are several important considerations before using Omtralo.
Who Should Not Take Omtralo
Do not use Omtralo if you are allergic to its ingredients, are pregnant, have severe liver disease, or are taking certain other medications like ACE inhibitors.
Medical Conditions to Discuss
Discuss with your doctor if you have low blood pressure, kidney problems, or are taking medications that affect potassium levels.
Pregnancy and Breastfeeding
Do not take Omtralo if you are pregnant or planning to become pregnant. If you become pregnant while on this medication, inform your doctor immediately. Consult your doctor if you are breastfeeding.
Elderly Patients With Dementia: Special caution is advised for elderly patients with dementia.
Drug Interactions
Certain medications may interact with Omtralo and affect its efficacy.
- ACE inhibitors
- ARBs
- Statins (e.g., atorvastatin)
- Sildenafil
- Potassium-sparing diuretics (e.g., amiloride)
- NSAIDs (e.g., ibuprofen)
- Lithium
- Frusemide
- Metformin
- Certain antibiotics (e.g., rifampicin)
- Ciclosporin
- Ritonavir
Alcohol & Driving
Be cautious with alcohol consumption and operating machinery while taking Omtralo.
Alcohol
There are no known interactions between Omtralo and alcohol, but it's best to be cautious.
Driving and Operating Machinery
Omtralo may cause dizziness or tiredness, so be careful when driving or using machinery.
Storage
Store Omtralo in a cool, dry place away from moisture, heat, and sunlight. Keep it out of reach of children.
Overdose Information
If you suspect an overdose, seek immediate medical attention. Symptoms may include dizziness or lightheadedness. Contact the Poisons Information Centre at 13 11 26 or go to the nearest hospital.
Frequently Asked Questions
Omtralo may take several weeks to show its full effect in managing heart failure.
You can take Omtralo with or without food.
No, Omtralo is not considered addictive.
Do not stop taking Omtralo suddenly without consulting your doctor, as it may worsen your condition.
There are no known interactions between Omtralo and alcohol, but it's advisable to be cautious.
Weight gain is not specifically mentioned as a side effect of Omtralo.
Elderly patients should use Omtralo with caution, especially if they have dementia.
If you miss a dose, take it as soon as you remember, but skip it if it's almost time for your next dose.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.