Monurol (Fosfomycin Trometamol)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Monurol Used For?
Monurol is a single-dose antibiotic specifically designed to treat uncomplicated urinary tract infections in women.
Primary Uses
Monurol is used to treat uncomplicated urinary tract infections in females caused by bacteria.
How It Works
Monurol contains fosfomycin trometamol, an antibiotic that works by killing E. coli and E. faecalis bacteria that can cause urinary tract infections.
Good to know: Monurol is a convenient single-dose treatment that you only need to take once.
How to Take Monurol
Monurol comes as a powder in a sachet that you dissolve in water and drink as a single dose.
Dosage Instructions
Take one sachet of Monurol dissolved in a glass of cold water. Take it on an empty stomach (2-3 hours before or after a meal), preferably before going to bed and after emptying your bladder. Do not use hot water to dissolve the powder. Drink the solution immediately after mixing.
What If You Miss a Dose?
If you forget to take Monurol after filling your prescription, take it the very next day.
Important: Take Monurol on an empty stomach and after emptying your bladder for best results.
Available Tablet Strengths
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Headache
- Dizziness
- Diarrhea
- Nausea
- Vomiting
- Indigestion
- Female genital infection with inflammation, irritation, or itching
- Abdominal pain
- Rash, hives, or itching
Seek immediate medical attention if you experience:
- Mild to severe abdominal cramps with bloody stools, diarrhea and/or fever (may indicate antibiotic-associated colitis)
- Sudden rash, itching, hives, shortness of breath, wheezing, or difficulty breathing
- Swelling of face, lips, tongue, or throat with breathing difficulties (allergic reaction)
Important Warnings
There are important safety considerations before taking Monurol that you should discuss with your healthcare provider.
Who Should Not Take Monurol
Do not take Monurol if you are allergic to fosfomycin trometamol or any ingredients in the medication. Do not give to children under 12 years old. Not recommended if you have severely reduced kidney function (creatinine clearance below 10 ml/min).
Medical Conditions to Discuss
Tell your doctor if you have allergies to other medicines, foods, preservatives or dyes; intolerance to some sugars; history of diarrhea after taking antibiotics; or reduced kidney function (but creatinine clearance above 10 ml/min).
Pregnancy and Breastfeeding
Check with your doctor if you are pregnant or planning to become pregnant. The active ingredient can cross the placenta and may affect your baby. Monurol passes into breast milk and may affect a breastfeeding baby. Tell your doctor immediately if you become pregnant while taking this medicine.
Drug Interactions
Some medications and products can interfere with how Monurol works or be affected by it.
Important: Avoid urinary alkalinizers and acidic drinks like cranberry juice while taking Monurol as they may interfere with the medication’s effectiveness.
- Metoclopramide and other drugs that increase stomach movement may reduce Monurol absorption
- Anticoagulants (blood thinners) may have altered effectiveness
- Urinary alkalinizers (like Ural) can interfere with how Monurol works
- Acidic drinks like cranberry juice may interfere with Monurol’s effectiveness
Alcohol & Driving
Monurol may affect your ability to drive or operate machinery, and you should inform your doctor about alcohol consumption.
Alcohol
Tell your doctor if you drink alcohol while taking Monurol.
Driving and Operating Machinery
Monurol may cause dizziness in some people. If you experience dizziness, do not drive, operate machinery, or do anything else that could be dangerous until you know how the medication affects you.
Storage
Keep your Monurol sachet in the original carton until you’re ready to take it. Store in a cool, dry place away from moisture, heat, and sunlight. Do not store in the bathroom, near a sink, in the car, or on windowsills. Keep out of reach of children.
Overdose Information
If you think you have taken too much Monurol, seek urgent medical attention immediately. Call the Poisons Information Centre at 13 11 26, contact your doctor, or go to the nearest hospital Emergency Department, even if you don’t feel unwell.
Frequently Asked Questions
Monurol is a single-dose antibiotic that works by killing bacteria causing urinary tract infections. You should follow up with your doctor if symptoms don’t improve.
No, Monurol should be taken on an empty stomach, 2-3 hours before or after a meal, preferably before bed and after emptying your bladder for best effectiveness.
No, Monurol is designed as a single-dose treatment. You only need to take one sachet dissolved in water.
If you forget to take Monurol after filling your prescription, take it the very next day.
No, acidic drinks like cranberry juice may interfere with how Monurol works and are not recommended while taking this medication.
Check with your doctor if you are pregnant or planning to become pregnant. The medication can cross the placenta and may affect your baby. Tell your doctor immediately if you become pregnant while taking Monurol.
If diarrhea becomes severe, consult your doctor immediately. Severe abdominal cramps, bloody stools, diarrhea and/or fever may indicate a serious intestinal infection requiring immediate medical attention.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.