Misty-Duo Allergy (Azelastine Hydrochloride And Fluticasone Propionate)
Complete patient guide for uses, dosage, side effects, and safety information
Prescription RequiredQuick Facts
What Is Misty-Duo Allergy Used For?
Misty-Duo Allergy is a nasal spray that combines two active ingredients to effectively treat moderate to severe allergic rhinitis (hayfever) in adults and children 12 years and older.
Primary Uses
Treats moderate to severe allergic rhinitis (hayfever and other allergies). Relieves sneezing and runny, itchy or blocked nose. Can be used for seasonal allergies (spring/summer due to pollens) or year-round allergies (caused by house dust mites, pets, or moulds).
How It Works
Contains azelastine hydrochloride (an antihistamine) that prevents the effects of histamine produced during allergic reactions, and fluticasone propionate (a corticosteroid) that helps reduce inflammation in the nose lining.
Good to know: While the antihistamine effect is rapid, it may take several days for the full anti-inflammatory action to take effect. Regular use helps prevent symptoms from returning quickly.
How to Take Misty-Duo Allergy
Misty-Duo Allergy is a nasal spray that should be used regularly for best results. Proper technique is important to ensure you get the right dose.
Dosage Instructions
Adults and adolescents (12 years and older): One spray into each nostril in the morning and evening. Adolescents from 12-17 years should only use on advice from a doctor. Not recommended for children under 12 years. Should not be used for more than 6 months except on doctor’s advice.
What If You Miss a Dose?
If it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Do not take a double dose to make up for the missed dose.
Important: Never use a double dose to make up for a missed dose. Keep your head tilted downwards (not backwards) when using to prevent medicine going into your throat and causing unpleasant taste.
Side Effects
Like all medications, this medicine can cause side effects. Most are mild and temporary, but some require medical attention.
Common Side Effects
These side effects occur relatively frequently and usually don’t require emergency care:
- Irritated nose (mild stinging, itching or sneezing)
- Bitter or unpleasant taste in mouth
- Unpleasant smell
- Cough, dry throat or throat irritation
- Sore throat
- Nose bleeds
- Nausea
- Headache
Seek immediate medical attention if you experience:
- Sleepiness or drowsiness
- Feeling weary, exhausted or weak
- Damage of the skin and mucous membrane in the nose
- Blurred vision or increased pressure in your eye
- Sudden signs of allergy (rash, itching, hives, swelling of face/lips/tongue, shortness of breath, wheezing, trouble breathing)
Important Warnings
Before using Misty-Duo Allergy, it’s important to discuss your medical history and current medications with your doctor or pharmacist.
Who Should Not Take Misty-Duo Allergy
Do not use if you are allergic to azelastine hydrochloride, fluticasone propionate, or any other ingredients. Do not use if the medicine has expired or if tamper evident packaging is damaged.
Medical Conditions to Discuss
Tell your doctor if you have: recent injury or surgery to nose or mouth, infection in nose or sinus, ulcer or open sores in nose, active or inactive tuberculosis, severe liver disease, increased/high pressure in the eye (glaucoma) and/or cataracts, or allergies to other medicines, foods, preservatives or dyes.
Pregnancy and Breastfeeding
Check with your doctor if you are pregnant or intend to become pregnant. Talk to your doctor if you are breastfeeding or intend to breastfeed. It is not known if Misty-Duo Allergy passes into breast milk and could affect your baby.
Benzalkonium Chloride: Contains benzalkonium chloride which may cause irritation or swelling inside the nose, especially if used for a long time.
Drug Interactions
Some medicines may interfere with Misty-Duo Allergy and affect how it works. Always tell your doctor about all medicines you’re taking.
Important: You may need different amounts of your medicine, or you may need to use a different medicine. Your doctor or pharmacist will advise you.
- Medicines that depress the central nervous system (may cause sleepiness or drowsiness)
- Ritonavir (antiviral medicine)
- Ketoconazole (antifungal medicine)
- Cimetidine (medicine that inhibits stomach acid production)
Alcohol & Driving
Misty-Duo Allergy is unlikely to make you feel drowsy, but caution is still advised when driving or operating machinery.
Alcohol
Alcohol intake may make drowsiness worse if you experience this side effect.
Driving and Operating Machinery
Be careful before you drive or use any machines or tools until you know how Misty-Duo Allergy affects you. If you are tired, drowsy, dizzy or lightheaded, do not drive a car or operate machinery.
Storage
Keep Misty-Duo Allergy in a cool dry place where the temperature stays below 25°C. Do not refrigerate or freeze this medicine. Store away from moisture, heat or sunlight – not in the bathroom, near a sink, in the car or on window sills. Keep where young children cannot reach it. Discard after 6 months of first opening the bottle.
Overdose Information
If you think you have used too much Misty-Duo Allergy on one occasion, there is nothing to worry about. However, using too much over a long time (months or years) may cause unwanted side effects. Immediately phone the Poisons Information Centre (13 11 26), contact your doctor, or go to the Emergency Department at your nearest hospital, even if there are no signs of discomfort or poisoning.
Frequently Asked Questions
While the antihistamine effect (azelastine) is rapid, it may take several days for the full anti-inflammatory action (fluticasone) to take effect. Regular use helps prevent symptoms from returning quickly.
Misty-Duo Allergy should not be used for more than 6 months except on the advice of a doctor.
If it’s almost time for your next dose, skip the missed dose and take your next dose when scheduled. Do not use a double dose to make up for the missed dose.
This medicine is not recommended for children under 12 years. Adolescents from 12-17 years should only use it on advice from a doctor.
See your doctor or pharmacist if your nose bleeds, as this is listed as a side effect that should be monitored.
Keep in a cool dry place where temperature stays below 25°C. Do not refrigerate or freeze. Discard after 6 months of first opening the bottle.
Alcohol intake may make drowsiness worse if you experience this side effect from the medication.
Important Disclaimer
This information is intended for general educational purposes only and should not be considered medical advice. Always consult your healthcare provider or pharmacist before starting, stopping, or changing any medication.
If you think you may have a medical emergency, call your doctor or emergency services immediately.